Best Justin Jefferson prop bet for Vikings vs. Bills on Monday 11/09/26

Justin Jefferson has every reason to be exasperated with Minnesota’s offense. He caught five passes for 33 yards in Detroit, bringing him to 335 yards through six appearances this season. One of those outings ended early with an injury. The receiver called the offense’s potential “very, very special” and lamented how much of it the Vikings have wasted. He also made clear that he still believes in Kyler Murray. With Murray sidelined by a hamstring injury, Carson Wentz gets the next chance to unlock Jefferson.

Below is my favorite way to attack Jefferson’s market for tonight’s MNF tilt against the Bills.

Here’s how I’ll play it. I’ll be pumping out these predictions for individual games all season, with plenty of coverage here on DraftKings Network. Follow my handle @dansby_edits for more betting plays.

Most all stats provided by Fantasy Points Data Suite 2.0.

Justin Jefferson’s best prop for Monday Night Football vs. Bills

Justin Jefferson o78.5 total receiving yards (-110)

Wentz’s and Jefferson’s recent work together gives me plenty to like. Across seven games in which Wentz has played since last season, Jefferson has commanded 31.5% of Minnesota’s targets and 45.2% of the air yards. He has averaged 87.6 receiving yards and produced 2.52 yards per route in that sample. Wentz has given him room to build a big statline through downfield work.

Buffalo’s coverage presents another opening. The Bills have played Cover 3 or Cover 4 on 58% of their defensive snaps in our matchup research; Jefferson has produced 3.38 yards per route against those coverages across 63 routes. Minnesota averages only 33 dropbacks per game, so empty possessions could leave him short. Give Jefferson his share of those throws, though, and I like his chances of finally breaking loose.

Best prop: Justin Jefferson o78.5 total receiving yards (-110)