There is a great Thursday Night Football matchup in Week 7 of the NFL season. The Chicago Bears host the New England Patriots in a great primetime matchup.
Here are my top Pick6 plays for Thursday Night Football.
Bears vs. Patriots DraftKings Pick6 Picks for Thursday Night Football
Caleb Williams More Than 219.5 Passing Yards (Promo Pick)

There are some great promo picks available on DraftKings Pick6 for Thursday Night Football. My favorite promo pick is on Caleb Williams to throw for more than 219.5 passing yards. This line is cut down 30 yards from the original line of 249.5 passing yards. It has been a bit of a tough start to the season for Williams. He had to miss some time after getting injured against the Vikings. However, in the two games Williams has played in full, he has comfortably cleared this number. Williams threw for 269 yards in Week 1 against the Panthers and for 305 yards in his return last week against the Falcons. New England ranks 13th in defensive EPA/dropback, so while a solid unit, there is certainly room to attack it. Williams should get over this number at home.
Drake Maye Less Than 29.5 Rushing Yards

Drake Maye is a solid runner from the quarterback position. However, he has not been running at the same rate this season. Maye ran a lot more often earlier in his career. This season, he is averaging just 5.7 carries per game. In four of his past five games, he has rushed for 25 yards or less. That trend should continue against the Bears. Chicago has a good pass rush, ranking fifth in the NFL in sacks this season. Maye should be forced to get the ball out quickly, rather than running around creating plays with his legs. The Bears are allowing just 11.7 rushing yards per game to opposing quarterbacks this season. They should keep that success of containing quarterbacks going and limit Maye to less than 29.5 rushing yards.
D’Andre Swift More Than 0.5 Rush + Rec Touchdowns

D’Andre Swift is having a solid season with the Bears. He ranks 11th in the NFL in rushing yards and seventh in rushing touchdowns. Swift has three touchdowns over his past two games and should keep that momentum going against the Patriots. The way to attack New England this season is on the ground. The Patriots rank 24th in the NFL in defensive EPA/rush and 22nd in opponent rushing touchdown percentage. New England has given up 41.7% of its touchdowns on the ground this season. Roschon Johnson lost a pivotal fumble last week, and he could see his workload decreased a bit. Kyle Monangai is likely out another week, meaning Swift should get the lion’s share of the carries. D’Andre Swift should find the end zone for the third straight game in this matchup against New England.
What is DraftKings Pick6?
Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of 2+ players and select whether you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.
How to Play
Create a Pick Set
Create a Pick Set by choosing 2+ players from the same sport and Pick Group (a set of picks available from a group of set competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you cannot pick the same player twice, and you must pick players from at least two different teams.
Enter an Amount
Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.
Sweat Your Picks
When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.
Compete for Prizes
Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.
Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!
- Chicago Bears vs. New England Patriots prediction, pick for NFL Week 7 on Thursday 10/22/26
- Patriots vs. Bears NFL DFS Showdown Picks and Strategy for Thursday Night Football
- Thursday Night Football Parlay Trends: New England Patriots vs. Chicago Bears 10/22/26
- Is Caleb Williams back to must-start fantasy football status?
- Is A.J. Brown the best buy-low fantasy football trade target for Week 7?