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NFL Week 1 Parlays: Best Bets for Sunday

NFL Week 1 Parlays: Best Bets for Sunday

Published:

By: Steve Buchanan

Looking for the best NFL Week 1 parlays for Sunday? This page features DraftKings Sportsbook parlay cards from the Sunday main slate, including anytime touchdown scorer, passing yards, receiving yards, rushing yards and rushing plus receiving yards bets.

These Sunday parlay bets combine player selections from across the slate. Browse the touchdown scorer and player prop parlays below, or check out our NFL Week 1 picks and predictions for straight-up game analysis.

Jump to: Anytime touchdown scorer parlays | Receiving yards parlays | Rushing yards parlays | Rushing + receiving yards parlays | Passing yards parlays

Anytime Touchdown Scorer Parlay: Big-Time Playmakers

This anytime touchdown scorer parlay features four productive offensive stars from the 2025 season. Jonathan Taylor led the NFL with 18 rushing touchdowns, Jahmyr Gibbs added 13 on the ground, Bijan Robinson rushed for 1,478 yards and Ja’Marr Chase caught eight touchdown passes.

  • Jahmyr Gibbs anytime touchdown scorer
  • Bijan Robinson anytime touchdown scorer
  • Ja’Marr Chase anytime touchdown scorer
  • Jonathan Taylor anytime touchdown scorer
Parlay

Big-Time Playmakers

Select some of the NFL's best offensive weapons to find the end zone

Odds: +510

Jahmyr Gibbs to Score a TD Anytime TD Scorer (Anytime Scorer)
Bijan Robinson to Score a TD Anytime TD Scorer (Anytime Scorer)
Ja'Marr Chase to Score a TD Anytime TD Scorer (Anytime Scorer)
Jonathan Taylor to Score a TD Anytime TD Scorer (Anytime Scorer)
Ends in: --:--
Bet Count: 2183
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Anytime Touchdown Scorer Parlay: Shifty Backs!

This anytime touchdown scorer parlay is built around four versatile running backs. Bijan Robinson rushed for 1,478 yards and seven touchdowns in 2025, while Breece Hall added 1,065 rushing yards before joining D’Andre Swift and Chase Brown on this card.

  • D’Andre Swift anytime touchdown scorer
  • Bijan Robinson anytime touchdown scorer
  • Breece Hall anytime touchdown scorer
  • Chase Brown anytime touchdown scorer
Parlay

Shifty Backs!

Select each of these top RBs to score 1+ TD in Sunday's action

Odds: +984

D'Andre Swift to Score a TD Anytime TD Scorer (Anytime Scorer)
Bijan Robinson to Score a TD Anytime TD Scorer (Anytime Scorer)
Breece Hall to Score a TD Anytime TD Scorer (Anytime Scorer)
Chase Brown to Score a TD Anytime TD Scorer (Anytime Scorer)
Ends in: --:--
Bet Count: 143
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Quarterback Anytime Touchdown Scorer Parlay: Scramble Mode

This anytime touchdown scorer parlay backs three mobile quarterbacks. Jalen Hurts, Jayden Daniels and Malik Willis each offer a rushing path to the end zone.

  • Jalen Hurts anytime touchdown scorer
  • Jayden Daniels anytime touchdown scorer
  • Malik Willis anytime touchdown scorer
SGPx

Scramble Mode

Back these dynamic QBs to find the end zone in Week 1

Odds: +3300

Jalen Hurts to Score a TD Anytime TD Scorer (Anytime Scorer)
Jayden Daniels to Score a TD Anytime TD Scorer (Anytime Scorer)
Malik Willis to Score a TD Anytime TD Scorer (Anytime Scorer)
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Bet Count: 121

Anytime Touchdown Scorer Parlay: Pardon My Take

Pardon My Take is backing this three-leg anytime touchdown scorer parlay. DeVonta Smith enters the season after recording 1,008 receiving yards and four touchdowns in 2025, while Aaron Jones and Michael Mayer complete the card.

  • DeVonta Smith anytime touchdown scorer
  • Aaron Jones anytime touchdown scorer
  • Michael Mayer anytime touchdown scorer
Parlay

Pardon My Take

Ride with the PMT crew as they pick their favorite TD scorers this week!

Odds: +2518

DeVonta Smith to Score a TD Anytime TD Scorer (Anytime Scorer)
Aaron Jones to Score a TD Anytime TD Scorer (Anytime Scorer)
Michael Mayer to Score a TD Anytime TD Scorer (Anytime Scorer)
Ends in: --:--
Bet Count: 2492
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Receiving Yards Parlay: Route Tacticians

This receiving yards parlay targets five primary pass catchers. DeVonta Smith and Trey McBride both topped 1,000 receiving yards in 2025, while Justin Jefferson, Christian Watson and Terry McLaurin round out the card at varying yardage thresholds.

  • Justin Jefferson 80+ receiving yards
  • DeVonta Smith 70+ receiving yards
  • Christian Watson 60+ receiving yards
  • Trey McBride 50+ receiving yards
  • Terry McLaurin 40+ receiving yards
SGPx

Route Tacticians

Bank on these standouts to hit their receiving yards milestones

Odds: +1668

Justin Jefferson 80+ Receiving Yards Justin Jefferson Receiving Yards
DeVonta Smith 70+ Receiving Yards DeVonta Smith Receiving Yards
Christian Watson 60+ Receiving Yards Christian Watson Receiving Yards
Trey McBride 50+ Receiving Yards Trey McBride Receiving Yards
Terry McLaurin 40+ Receiving Yards Terry McLaurin Receiving Yards
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Receiving Yards Parlay: Bama Boys

This receiving yards parlay backs four former Alabama wide receivers to clear 50 yards. DeVonta Smith, Jameson Williams and Jaylen Waddle each topped 900 receiving yards in 2025, with Jerry Jeudy completing the Crimson Tide group.

  • DeVonta Smith 50+ receiving yards
  • Jameson Williams 50+ receiving yards
  • Jaylen Waddle 50+ receiving yards
  • Jerry Jeudy 50+ receiving yards
Parlay

Bama Boys

Take these former Alabama Crimson Tide WRs to dominate in Week 1

Odds: +1249

DeVonta Smith 50+ Receiving Yards DeVonta Smith Receiving Yards
Jameson Williams 50+ Receiving Yards Jameson Williams Receiving Yards
Jaylen Waddle 50+ Receiving Yards Jaylen Waddle Receiving Yards
Jerry Jeudy 50+ Receiving Yards Jerry Jeudy Receiving Yards
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Bet Count: 199
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Rushing Yards Parlay: Run It Up

This rushing yards parlay features four running backs. Saquon Barkley and De’Von Achane each topped 1,100 rushing yards in 2025, while Omarion Hampton and Jordan Mason have lower rushing-yard thresholds to complete the card.

  • Saquon Barkley 80+ rushing yards
  • De’Von Achane 70+ rushing yards
  • Omarion Hampton 60+ rushing yards
  • Jordan Mason 50+ rushing yards
Parlay

Run It Up

Ride these stars to keep the chains moving and reach their rushing milestones!

Odds: +1165

Saquon Barkley 80+ Rushing Yards Saquon Barkley Rushing Yards
De'Von Achane 70+ Rushing Yards De'Von Achane Rushing Yards
Omarion Hampton 60+ Rushing Yards Omarion Hampton Rushing Yards
Jordan Mason 50+ Rushing Yards Jordan Mason Rushing Yards
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Rushing + Receiving Yards Parlay: Workhorse Backs

This rushing and receiving yards parlay targets three backs who can produce as runners and pass catchers. Saquon Barkley rushed for 1,140 yards in 2025, while De’Von Achane posted 1,350 rushing yards as Omarion Hampton joins them to clear 100 combined rushing and receiving yards.

  • Saquon Barkley 100+ rushing and receiving yards
  • Omarion Hampton 100+ rushing and receiving yards
  • De’Von Achane 100+ rushing and receiving yards
Parlay

Workhorse Backs

Pick Barkley, Hampton & Achane to dominate on the ground and as a pass catcher

Odds: +760

Saquon Barkley 100+ Rush + Rec Yards Saquon Barkley Rushing + Receiving Yards
Omarion Hampton 100+ Rush + Rec Yards Omarion Hampton Rushing + Receiving Yards
De'Von Achane 100+ Rush + Rec Yards De'Von Achane Rushing + Receiving Yards
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Passing Yards Parlay: Back in the Day

This passing yards parlay brings together three former Offensive Rookies of the Year. Jayden Daniels, Justin Herbert and Kyler Murray each need to throw for 250 or more yards.

  • Jayden Daniels 250+ passing yards
  • Justin Herbert 250+ passing yards
  • Kyler Murray 250+ passing yards
Parlay

Back in the Day

Take these former Offensive Rookies of the Year to throw for 250+ yards

Odds: +2463

Jayden Daniels 250+ Passing Yards Jayden Daniels Passing Yards
Justin Herbert 250+ Passing Yards Justin Herbert Passing Yards
Kyler Murray 250+ Passing Yards Kyler Murray Passing Yards
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Passing Yards Parlay: Sophomore Surge

This passing yards parlay focuses on three second-year quarterbacks. Tyler Shough, Cameron Ward and Jaxson Dart each need to throw for 250 or more yards.

  • Tyler Shough 250+ passing yards
  • Cameron Ward 250+ passing yards
  • Jaxson Dart 250+ passing yards
Parlay

Sophomore Surge

Take these 2nd-year QBs to start their seasons off strong!

Odds: +2551

Tyler Shough 250+ Passing Yards Tyler Shough Passing Yards
Cameron Ward 250+ Passing Yards Cameron Ward Passing Yards
Jaxson Dart 250+ Passing Yards Jaxson Dart Passing Yards
Ends in: --:--
Bet Count: 118
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NFL Parlays FAQ

What are the best anytime touchdown scorer parlays for NFL Week 1?

Anytime touchdown scorer parlays combine players from different games to score a touchdown. The cards above feature running backs, wide receivers and mobile quarterbacks, including Jahmyr Gibbs, Bijan Robinson, Ja’Marr Chase, Jonathan Taylor, Jalen Hurts and Jayden Daniels.

What NFL player props are good for Sunday parlays?

Passing yards, receiving yards, rushing yards and combined rushing plus receiving yards are all available for Sunday NFL player prop parlays. The cards above range from 250-plus passing yards to lower receiving and rushing yardage milestones.

How do you build a multi-game NFL parlay?

A multi-game NFL parlay combines bets involving players or teams from more than one game. The parlay cards on this page combine multiple player selections into one bet, with the available markets displayed on each DraftKings Sportsbook card.

Can NFL parlay odds change before kickoff?

Yes. NFL parlay odds and available player prop markets can change before kickoff. Check the DraftKings Sportsbook parlay card for the latest available selections.

All views expressed are my own. I am an employee of DraftKings and am ineligible to play in public DFS or DKSB contests.