DraftKings Sportsbook has a full lineup of MLB parlays and same game parlays for Friday, September 26, 2025. Below you’ll find our top MLB parlay picks today, including same game parlay options built for tonight’s matchups. You can instantly add any of these to your bet slip with the “Add to Bet Slip” button.
You can view our full complement of parlays and same game parlays on DraftKings Network!
MLB September 26, 2025 Same Game Parlay and SGP Picks on DraftKings
David Ortiz Friday Picks: Red Sox Legend David Ortiz is backing these two players to hit a home run on Friday
- Cal Raleigh to hit a home run
- Shohei Ohtani to hit a home run
No Run First Inning Parlay: Root for NRFI in these four games on Friday!
- Tampa Bay Rays @ Toronto Blue Jays No Run First Inning
- New York Mets @ Miami Marlins No Run First Inning
- Texas Rangers @ Cleveland Guardians No Run First Inning
- Pittsburgh Pirates @ Atlanta Braves No Run First Inning
Two Total Bases Parlay: Back these sluggers to record at least 2+ total bases on Friday Night!
- Kyle Schwarber 2+ Total Bases
- Aaron Judge 2+ Total Bases
- Francisco Lindor 2+ Total Bases
- Vladimir Guerrero 2+ Total Bases
Home Run Parlay: Bet these two New York sluggers to hit a home run
- Aaron Judge to hit a home run
- Juan Soto to hit a home run
Detroit Tigers SGP: The Tigers are vying for a playoff spot, back them tonight
- Detroit Tigers to win (@Boston Red Sox)
- Riley Greene 3+ H/R/RBI
- Gleyber Torres 3+ H/R/RBI
- Spencer Torkelson 3+ H/R/RBI
1+ RBI Parlay: Bet these players to knock in at least one RBI
- Josh Bell 1+ RBI
- Kyle Schwarber 1+ RBI
- Aaron Judge 1+ RBI
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Want even more action? Check out all of our MLB parlays on DraftKings Network for updated odds and fresh builds.
MLB Schedule — September 26, 2025
As part of our MLB Parlays & SGP Picks on DraftKings for September 26, 2025, here’s a look at today’s full MLB schedule with start times for every matchup.
- Twins @ Phillies — 6:45 PM
- White Sox @ Nationals — 6:45 PM
- Orioles @ Yankees — 7:05 PM
- Rays @ Blue Jays — 7:07 PM
- Tigers @ Red Sox — 7:10 PM
- Mets @ Marlins — 7:10 PM
- Rangers @ Guardians — 7:10 PM
- Pirates @ Braves — 7:15 PM
- Reds @ Brewers — 8:10 PM
- Astros @ Angels — 9:38 PM
- Diamondbacks @ Padres — 9:40 PM
- Dodgers @ Mariners — 9:40 PM
- Royals @ Athletics — 10:05 PM
- Rockies @ Giants — 10:15 PM
