At long last, football season is officially underway. And as if to commemorate the occasion, 26 teams are kicking off their seasons on the first NFL Sunday of 2026.
In the Midwest, the Indianapolis Colts will host the Baltimore Ravens for an AFC matchup at Lucas Oil Stadium, with kickoff scheduled for 1 p.m. ET.
Both teams are hoping for better seasons — and healthier quarterbacks — than they had in 2025. The Ravens missed the playoffs for just the second time in the last eight years, as Lamar Jackson missed time to nurse multiple injuries. The Colts emerged as early Super Bowl contenders before the resurgent Daniel Jones tore his Achilles in Week 14, and the team failed to win a single game in his absence.
Baltimore is a 3.5-point road favorite with -175 moneyline odds on DraftKings Sportsbook. Indianapolis is a +145 underdog, with the game total set at O/U 47.5 points.
Let’s dive into the top player prop bets for Sunday’s clash between the Ravens and the Colts.
Ravens vs. Colts NFL Player Prop Bets
Jonathan Taylor Anytime Touchdown (-175)
Indy’s Jonathan Taylor is looking to build off a dominant 2025 campaign, during which he led the NFL with 18 rushing touchdowns — to go along with a pair of receiving scores. The superstar running back, 27, handled a league-best 323 carries for a whopping 1,585 yards — third-most in the sport.
Even with a returning Daniel Jones reinstating the pass game, Taylor should remain the Colts’ most reliable weapon in Sunday’s season opener against the Ravens.
After their trade for Maxx Crosby fell apart at the eleventh hour, the Ravens settled for the next-best thing: former Bengals linebacker Trey Hendrickson. With a bolstered pass rush, Baltimore will be looking to pressure Jones from the first snap. However, Hendrickson’s presence doesn’t necessarily shore up the team’s run defense — which allowed the NFL’s 10th-most rushing touchdowns in 2025 (18).
Lamar Jackson 8+ Rush Attempts (+146)
A healthy Lamar Jackson is a dangerous Lamar Jackson. When his nagging injuries weren’t keeping him on the sidelines last year, they were restricting his mobility. But the two-time MVP looks ready to go for 2026, emphasizing that he’s willing to do “whatever it takes to win.”
That includes the run game. One of the most dynamic field generals the sport has ever seen, Jackson averaged north of eight rush attempts per game every year from 2018 to 2024 — with a high of 11.08 carries per contest in 2021. The Louisville product, 29, has churned the second-most rushes for a QB in NFL history (1,081) into the most rush yards ever produced from under center (6,522).
While the Colts arrive with a stout rush defense, Jackson has a special knack for making even the strongest coverages appear porous. With a fresh set of legs, the superstar QB should be comfortable and eager to hit the jets in Sunday’s season opener.