The 2025 regular season is complete. No more meaningless games filling weekend slates. Each game moving forward is a must-win and holds significant weight.
The best of the best earned byes through Wild Card Weekend, but the rest of the playoff teams will compete for their spot in the divisional round. The matchups are set, and DraftKings Sportsbook has you covered with the latest odds for each game.
Here’s a breakdown of each 2026 Wild Card Weekend matchup with odds from DraftKings Sportsbook.
Saturday Games, Jan. 10
Rams vs. Panthers – 4:30 p.m. ET
Odds on Sunday, Jan. 4
| Spread | Total | Moneyline | |
| LA Rams | -10 -115 | O 46.5 -110 | -675 |
| CAR Panthers | +10 -105 | U 46.5 -110 | +490 |
Not all playoff games will be close, and this is one of those matchups. The Rams finished 12-5 in the toughest division in football: the NFC West. Meanwhile, the Panthers squeaked into the postseason at 8-9. Home-field advantage is a plus for Carolina at least.
Packers vs. Bears – 8 p.m. ET
Odds on Sunday, Jan. 4
| Spread | Total | Moneyline | |
| GB Packers | +1.5 -122 | O 47.5 -110 | -110 |
| CHI Bears | -1.5 +102 | U 47.5 -110 | -110 |
It’s always fun seeing a division matchup in the postseason. Unlike other games, these teams are very familiar with each other. These squads split the season series, with the home team winning each round. Chicago gets home-field advantage in this bout.
Sunday Games, Jan. 11
Bills vs. Jaguars – 1 p.m. ET
Odds on Sunday, Jan. 4
| Spread | Total | Moneyline | |
| BUF Bills | -1.5 -102 | O 50.5 -110 | -118 |
| JAX Jaguars | +1.5 -118 | U 50.5 -110 | -102 |
The Bills failed to win their sixth straight AFC East title, so they fall to the No. 6 seed. Meanwhile, the Jaguars finished the season with eight straight victories to win the AFC South at 13-4.
49ers vs. Eagles – 4:30 p.m. ET
Odds on Sunday, Jan. 4
| Spread | Total | Moneyline | |
| SF 49ers | +3 -105 | O 46.5 -110 | +150 |
| PHI Eagles | -3 -115 | U 46.5 -110 | -180 |
The Eagles are the defending Super Bowl champions, but they don’t look as dominant as last year. Still, the team is 11-6 and has home-field advantage in this matchup vs. the 12-5 49ers.
Chargers vs. Patriots – 8 p.m. ET
Odds on Sunday, Jan. 4
| Spread | Total | Moneyline | |
| LA Chargers | +3.5 -110 | O 45.5 -110 | +154 |
| NE Patriots | -3.5 -110 | U 45.5 -110 | -185 |
This is a battle of two inexperienced squads. Justin Herbert is making his third career postseason start, while Drake Maye is making his debut. This is projected to be a tight No. 2 vs. No. 7 matchup.
Monday Game, Jan. 12
Steelers/Ravens vs. Texans – 8:15 p.m. ET
Odds on Sunday, Jan. 4
| Spread | Total | Moneyline | |
| HOU Texans | -2.5 -120 | O 39.5 -110 | -148 |
| PIT Steelers | +2.5 +100 | U 39.5 -110 | +124 |
The Texans ended the season on a nine-game win streak. This level of momentum is scary to face in the postseason, especially with Houston featuring one of the best defenses in the NFL. Meanwhile, the Steelers won a nail-biter to secure the final playoff spot.