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NFL Week 1: LeBron James’ Football Picks, Predictions

NFL Week 1: LeBron James’ Football Picks, Predictions

Updated:

By: Andy Silva

The NFL is back! And so is LeBron James, delivering his thoughts on the upcoming week of football action. Ahead of Week 1, James cast his NFL winner picks.


Dallas Cowboys at Philadelphia Eagles

LeBron likes the defending champs in the season opener on Thursday night. He says Jalen Hurts commands the game and he’s looking forward to seeing him back out there.

Pick: Eagles ML -410


Kansas City Chiefs at Los Angeles Chargers

LeBron points out that these two teams GO AT IT and he thinks the Chargers could be a sleeper team this season. He’s looking forward to another season of the Justin Herbert-Jim Harbaugh pairing in L.A. and LeBron is going with the Chargers in this one.

Pick: Chargers ML +142


Tampa Bay Buccaneers at Atlanta Falcons

LeBron likes the Bucs to roll into the ATL and come out with the W. He likes the group in Tampa Bay and what they bring bring to the table, especially defensively.

Picks: Buccaners ML -135


Cincinnati Bengals at Cleveland Browns

LeBron notes that if you’re looking to beat the Bengals, the best time to get them is early in the season. He knows Joe Burrow wants to change that, but to quote the great Lee Corso, “Not so fast, my friend.” LeBron is going with the Browns.

Picks: Browns ML +195


Miami Dolphins at Indianapolis Colts

Anthony Richardson will start the season as QB2 in Indy behind Daniel Jones, but LeBron is still riding with the Colts in Week 1 over Tua, Tyreek and the Dolphins.

Picks: Colts ML -112


Las Vegas Raiders at New England Patriots

LeBron thinks this could be an intriguing game, with the revamped Raiders — led by new coach Pete Carroll, new QB Geno Smith and rookie RB Ashton Jeanty — rolling into Foxboro to take on new addition Stefon Diggs, rookie RB TreVeyon Henderson from THE Ohio State University and the Patriots. As high as he is on the Pats, LeBron is going with the Silver and Black in this one.

Picks: Raiders ML +130


Arizona Cardinals at New Orleans Saints

Keeping it simple on this one — despite Marvin Harrison Jr. in the lineup for the Cardinals, LeBron is going with the Saints at home.

Picks: Saints ML +230


New York Giants at Washington Commanders

Jayden Daniels, Deebo Samuel and a solid Commanders defense will be too much for the Giants in LeBron’s eyes.

Picks: Commanders ML -265


Carolina Panthers at Jacksonville Jaguars

LeBron sees this one as a toss up, but he’s going with the home team in this one hoping a good crowd can get the Jags going. And hey, maybe we’ll get some Travis Hunter highlights in this one.

Picks: Jaguars ML -180


Tennessee Titans at Denver Broncos

LeBron thinks the Broncos could be good this season coming off a strong finish to last year and with Bo Nix entering his second season in Denver under head coach Sean Payton. Give LeBron the Broncos in this one.

Picks: Broncos ML -425


San Francisco 49ers at Seattle Seahawks

It’s always tough to roll into Seattle and contend with the 12th man, but LeBron is going with the 49ers in this one coming off an injury-filled 2024 campaign.

Picks: 49ers ML -142


Detroit Lions at Green Bay Packers

LeBron says we know how important this division rivalry game is for both teams, trying to one up one another from the jump in the NFC North standings. Micah Parson joining Jordan Love at Lambeau has LeBron saying, “Go, Pack, Go.”

Picks: Packers ML -148


Houston Texans at Los Angeles Rams

After missing time in training camp, Rams QB Matthew Stafford looks like he will be ready to go in Week 1. LeBron says he’s a beast, especially with Davante Adams now in Los Angeles. LeBron loves their defense as well, so give him the Rams.

Picks: Rams ML -155


Baltimore Ravens at Buffalo Bills

The Ravens and Bills have been battling the Chiefs for AFC supremacy in recent years and we all remember what happened last year in the postseason. LeBron is siding with the defending MVP Josh Allen and the Bills at home despite loving what Baltimore brings to the table.

Picks: Bills ML -112


Minnesota Vikings at Chicago Bears

LeBron says it’s simple — he’s thinking Jet. as in Justin “Jet” Jefferson. Give him Minnesota in the Monday Night Football opener.

Picks: Vikings ML -122


Check out King James’ NFL Moneyline parlay using our built-in parlay tool:

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Andy Silva has been with DraftKings since 2018. A 2006 graduate of the University of Connecticut, Andy worked as a copy editor for North of Boston Media Group and then the Boston Herald prior to joining DraftKings. He is a lifelong sneakerhead going back to the heyday of Michael Jordan in the 1990s. His all-time favorites are the Air Jordan 11 and the Air Max Penny 1. Follow him on Twitter at @ByAndySilva and on BlueSky at @byandysilva.bsky.social.
Disclaimer

All views expressed are my own. I am an employee of DraftKings and am ineligible to play in public DFS or DKSB contests.