At Highmark Stadium on Sunday, Nov. 17, the Buffalo Bills face the Kansas City Chiefs, kicking off at 4:25 p.m. ET. The Bills should win, based on our computer model — continue reading to find more tips about the point spread, over/under and even the final score.
Bills vs. Chiefs Predictions
- Our prediction to win on the Moneyline in this matchup is the Bills, by a final score of Bills 24, Chiefs 21.
- Against the spread, we expect that the Bills will cover. The spread is currently Bills -2.
- As for the total, it’s too close to call relative to the posted over/under of 46.
Bills vs. Chiefs Odds
- Spread favorite: Bills (-2)
- Moneyline: Bills (-130), Chiefs (+110)
- Total: 46 points
Bills Betting Trends
- The Bills have a 6-4-0 record against the spread this season.
- When it has played as at least 2-point favorites this season, Buffalo is 4-2 against the spread.
- Games involving the Bills have hit the over in six of their 10 games with a set total (60%).
- The Bills have yet to lose as the Moneyline favorite this season, going 7-0.
- Buffalo has played six times as a Moneyline favorite with odds of -130 or shorter, and won in each game.
Chiefs Betting Trends
- The Chiefs are 4-5-0 ATS this year.
- Kansas City is a perfect 1-0 against the spread when an underdog by 2 points or more this season.
- In the Chiefs’ nine games with a set total, four have hit the over (44.4%).
- The Chiefs won the only game they’ve played as the underdog this season.
- Kansas City has played as an underdog of +110 or more once this season and won that game.
Bills Key Stats
- Total offense: 343.2 yards per game, 14th in NFL
- Passing offense: 222.5 yards per game, 12th in NFL
- Rushing offense: 120.7 yards per game, 15th in NFL
- Total defense: 336.1 yards per game, 18th in NFL
- Passing defense: 212.9 yards per game, 18th in NFL
- Rushing defense: 123.2 yards per game, 15th in NFL
Chiefs Key Stats
- Total offense: 346.7 yards per game, 10th in NFL
- Passing offense: 231.6 yards per game, ninth in NFL
- Rushing offense: 115.1 yards per game, 21st in NFL
- Total defense: 289.9 yards per game, fourth in NFL
- Passing defense: 206.7 yards per game, 14th in NFL
- Rushing defense: 83.2 yards per game, third in NFL
This article contains AI-generated editorial insights provided by Data Skrive.
All odds provided by DraftKings Sportsbook and all odds subject to change.