Hello to the loyal Five Lists audience, as well as any new readers tuning in for the first time. We’re back once more to deliver your one-stop shop with all the fantasy football content you need to crush Week 4 of the NFL regular season. Whether it’s must-starts, breakouts, sleepers or stashes, it’s all here in this lovely column typically produced by our very own Dan Johnson. This ship’s captain is out of office at the moment (and will be back next week, so don’t worry), but in the meantime I’m taking the helm to guide us through the stormy seas of the fantasy landscape. To put your mind at ease — I bring the same sicko love for fantasy football and dedication to helping you win your week, just a slightly different voice. You’re in good hands!
It’s a pleasure to meet you all, but you didn’t click into this article to hear about me. You want the goods to win your fantasy matchups and I’ve got exactly what you’re looking for. See below for the Five Lists of Five: Week 4 WR/CB matchups to target. We’re talking receiver talent against poor secondaries with potential to pop off and escape the week with a booming performance.
Here are the other offerings from my 2025 Fantasy Football Five Lists of Five: Week 4 edition:
- Top five must-start players for Week 4 of 2025 fantasy football
- Top five breakout running backs for Week 4 of 2025 fantasy football
- Top five breakout wide receivers for 2025 fantasy football Week 4
- Top five players to stash for Week 4 of 2025 fantasy football
- BONUS LIST! Dynasty Fantasy Football Stock Watch: Top risers and fallers after Week 3
Follow my handle @keagreport for all of my fantasy football content.
Top five WR/CB matchups to target in 2025 fantasy football Week 4
Garrett Wilson vs. Dolphins secondary
There’s been a lot of talk over the last couple seasons about how great Garrett Wilson could be with a real quarterback under center. Well, the fourth-year standout ranks inside the top-12 fantasy football receivers with 18.6 FPPG through three weeks, including a pair of outings with 20+ points on the board. He ranks eighth in PFF receiving grade with the sixth-most targets (27), fourth-most receptions (21) and ninth-most yards (229) at the position while hauling in a pair of touchdowns. Wilson won’t wow with advanced metrics and his ADOT and after-catch numbers aren’t great, but he’s force-fed the ball as the top target in this Jets offense and has produced well with elite target share of 39.0%, the second-highest in football.
In Week 4, the Jets face the lowly Dolphins. Miami allows 225.3 passing yards per game, the 21st-worst mark, and an 0.41 defensive EPA/pass ranks dead-last among all franchises. Minkah Fitzpatrick is a great safety but this cornerback group appears ragtag — in PFF coverage grade, Rasul Douglas ranks 30th, Jack Jones 91st, and Jason Marshall Jr. 102nd of 102 qualifying players. The Dolphins run man coverage at the 10th-highest rate and Wilson averages 3.52 yards per route run against man looks. He produced in fantasy with Tyrod Taylor last week and can certainly repeat against an abysmal pass defense.
Rome Odunze vs. Raiders secondary
The breakout star of the 2025 campaign thus far, Rome Odunze looks like a real WR1-caliber talent at long last with 20.9 FPPG. He garners a 28.4% target share, 13th among all pass-catchers, and he ranks 11th in targets (25), 10th in receptions (16), 11th in receiving yards (227), and first in touchdowns with four. Odunze also posts top-30 marks in yards per reception, yards after the catch per reception and ADOT with the fourth-best passer rating when targeted. This second-year leap appears very, very real alongside an improved Caleb Williams in an offense called by Ben Johnson.
The Raiders are on deck this week with 237.0 passing yards allowed per contest, 24th, and the 27th-worst defensive EPA/pass at 0.19. Much like the Dolphins, Las Vegas deploys a nice safety in Jeremy Chinn but their corners are vulnerable. Kyu Blu Kelly ranks 68th in coverage grade, Eric Stokes sits 61st, and Darnay Holmes falls 84th. The secondary ranks 30th in yards allowed to wideouts, so Odunze and his teammates can post another big outing here as they did last week against the Cowboys.
Tetairoa McMillan vs. Patriots secondary
It seems a rookie wideout emerges every season as a legitimate star despite their inexperience. Through three games, Tetairoa McMillan looks every bit of the talent who was promised coming out of the draft as a first-round pick by the Panthers. For fantasy purposes, he averages 11.9 FPPG so far, but that total as well as his real-world statistic could’ve ended up higher had his team not blown out the Falcons 30-0 last week and coasted through the fourth quarter. A 73.9 receiving grade falls 15th in PFF’s rankings — McMillan sees the sixth-most targets (27), 22nd-most catches (14), and 14th-most receiving yards (216) of any wideout. He also slots in 16th in yards per reception with 15.4 despite a the 38th-highest ADOT at 11.3.
He’s a dude, plain and simple. The Panthers duel the Patriots on Sunday, who allow the 30th-most passing yards at 256.3 per game. The catch is that Christian Gonzalez, one of the game’s best young cornerbacks, likely returns from a hamstring injury this week. His status remains uncertain as does his projected snap share in his first game back in action this season, but Carlton Davis III and Marcus Jones come in at 54th and 65th in PFF coverage grade. If the team eases Gonzalez back into form, this matchup looks like another to love at 30th in defensive EPA/pass.
Keenan Allen vs. Giants secondary
Well, did anyone think Keenan Allen still had the juice after his one-off season with the Bears last year? The veteran receiver is back with the Chargers like he never even left, already converting key third downs and catching touchdowns from Justin Herbert like the teammates never spent a year apart. He falls 30st in routes run as L.A. protects his health but ranks sixth in targets (27), seventh in receptions (19), 19th in yards (194), and fourth in touchdowns with three. His 127.7 passer rating when targeted sits eighth among all wideouts with the 12th-best receiving grade in the NFL. Allen remains a very reliable fantasy weapon with 18.8 FPPG alongside Ladd McConkey and Quentin Johnston, even if he’s stolen some shine from the former.
The Chargers are airing the ball out so much that you probably don’t even need to worry about game script against a bad Giants team. Los Angeles’ +8.8% pass rate over expectation paces the entire league and they’ll sling the rock once more against rookie Jaxson Dart in his first start for New York. The Giants are 28th in passing yards allowed per game with 252.0 and 20th in defensive EPA/pass at 0.15. The trend of good safeties continues with the offseason acquisition of Jevon Holland, but Paulsen Adebo is still learning the scheme and falls 73rd in PFF coverage grade. Teammate Dru Phillips sits 82nd and projects to handle a significant workload against Allen, and while Cor’Dale Flott actually sees a ranking at 21st, PFF anticipates the latter sees just over seven snaps matched up with the veteran wideout. Wheels up, as they should be every week.
Courtland Sutton vs. Bengals secondary
Rounding out the final list of five, we’ve got Courtland Sutton of the Broncos. His 14.5 FPPG are a career-high through three weeks and a 23.6% target share doesn’t look bad by any means. He’s still the top wide receiver for Bo Nix in Sean Payton’s offense and remains a very consistent, if relatively unexciting talent. The PFF receiving grade of 70.2 only comes in at 31st, and the Broncos spread the ball around plenty. Sutton sits 24th in targets (21), 31st in catches (13) and 21st in yardage (185). However, he’s also scored two touchdowns with the 13th-best ADOT at 14.3. He doesn’t create much after the catch, but he’s a steady presence with soft hands and a proven ball-winner in contested situations.
You know the drill with the Bengals’ defense… 25th in passing yards allowed with 240.7, but surprisingly 12th in defensive EPA/pass at 0.07. Perhaps that’s because the team got gashed on the ground last week, but individual grades don’t really stand out. DJ Turner II and Cam Taylor-Britt tumble to 60th and 59th in PFF coverage grade and project to handle the majority of snaps against Sutton. Dax Hill actually sees the 14th-best grade, but probably won’t match up with him as much. There’s blowout potential here with Joe Burrow sidelined, so I like Sutton to post another quality day.
