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Best James Cook prop bet for Bills vs. 49ers on Sunday Night Football

Best James Cook prop bet for Bills vs. 49ers on Sunday Night Football

Published:

By: Dan Johnson

Christian McCaffrey, George Kittle, Deebo Samuel and the San Francisco 49ers will face the Buffalo Bills and quarterback Josh Allen, who’s fresh off an engagement to longtime girlfriend Hailee Steinfeld. It’s a desperation spot for the Niners in their ultra-competitive and still-up-for-grabs NFC West. It’s another opportunity for James Cook, Khalil Shakir, Dawson Knox &co. to show us that the Bills can let everyone eat on offense.

And I’ve got a James Cook prop I love.

Also, I liked upscaling an alt for Josh Allen’s rushing yards this week, and did the same for a Christian McCaffrey rush + reception total here.

Best James Cook prop bet for 49ers vs. Bills on Sunday Night Football

James Cook Anytime TD Scorer / Buffalo Bills to Win +120

Firstly, the Buffalo Bills are not losing this game tonight. This will be your quintessential lake-effect primetime win for Bills Mafia at home. The Niners simply don’t have enough support in their injured front-seven to stop the dynamic run game of Josh Allen and James Cook. Not to mention, I’d expect, because of the weather, lots of Allen’s pass plays to look like extensions of the run game to guys like Khalil Shakir and Dawson Knox.

Cook has ten touchdowns on the year, and has completely obliterated any concerns we’ve had about his goal line carries from 2023, when he only had four. His Anytime TD market is a little too cheap for me, so I’m going to hit this special that more-or-less parlays the Bills Moneyline with Cook hitting paydirt.

Bottom Line

Quintessential 2024 Joe Brady Buffalo Bills game. 50+ rushing yards for Josh Allen and at least a touchdown for James Cook. Bills by a million.

Best bet: James Cook Anytime TD Scorer / Buffalo Bills to Win +120


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All odds provided by DraftKings Sportsbook, lines and odds subject to change.


I am a promoter at DraftKings and am also an avid fan and user (my username is thegreatdansby9) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skill and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.

Dan Johnson has been an editor, writer, and analyst for DraftKings and DraftKings Network since 2024. He’s previously held editorial posts at The Paris Review, Macmillan Publishers, Bedford/St. Martin’s Press, ASSIGNMENT Magazine, and FantasySixPack. You can find his various editorial work & writing (sports-related and non-) at all of the above.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is thegreatdansby9) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.