Christian McCaffrey, George Kittle, Deebo Samuel and the San Francisco 49ers will face the Buffalo Bills and quarterback Josh Allen, who’s fresh off an engagement to longtime girlfriend Hailee Steinfeld. It’s a desperation spot for the Niners in their ultra-competitive and still-up-for-grabs NFC West. It’s another opportunity for James Cook, Khalil Shakir, Dawson Knox &co. to show us that the Bills can let everyone eat on offense.
And I’ve got a James Cook prop I love.
Also, I liked upscaling an alt for Josh Allen’s rushing yards this week, and did the same for a Christian McCaffrey rush + reception total here.
and you bet we’re taking a CMC prop tonight. the market for his rush + rec feels a bit uncertain, and i’m trying to capitalize on that
— Dan Johnson (@dansby_edits) December 1, 2024
again, over @DKNetwork https://t.co/0BX6ElxGDI
Best James Cook prop bet for 49ers vs. Bills on Sunday Night Football
James Cook Anytime TD Scorer / Buffalo Bills to Win +120
Firstly, the Buffalo Bills are not losing this game tonight. This will be your quintessential lake-effect primetime win for Bills Mafia at home. The Niners simply don’t have enough support in their injured front-seven to stop the dynamic run game of Josh Allen and James Cook. Not to mention, I’d expect, because of the weather, lots of Allen’s pass plays to look like extensions of the run game to guys like Khalil Shakir and Dawson Knox.

Cook has ten touchdowns on the year, and has completely obliterated any concerns we’ve had about his goal line carries from 2023, when he only had four. His Anytime TD market is a little too cheap for me, so I’m going to hit this special that more-or-less parlays the Bills Moneyline with Cook hitting paydirt.
Bottom Line
Quintessential 2024 Joe Brady Buffalo Bills game. 50+ rushing yards for Josh Allen and at least a touchdown for James Cook. Bills by a million.
Best bet: James Cook Anytime TD Scorer / Buffalo Bills to Win +120
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