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Full list of Week 12 straight-up picks with confidence levels

We make picks for a full week of NFL games with levels of confidence ahead of Week 12.

Dak Prescott #4 of the Dallas Cowboys on the field before a game against the Washington Commanders at AT&T Stadium on October 2, 2022 in Arlington, Texas. Photo by Wesley Hitt/Getty Images

The NFL is back for the first big holiday weekend of the season. Thanksgiving is upon us and that means a Thursday triple-header. This year also marks the first Black Friday game with the Dolphins and Jets facing off Friday afternoon.

The biggest game on the Thursday slate will see the Seahawks host the 49ers. San Francisco has a one-game lead in the NFC West and would take a potentially overwhelming lead in the division with a win. Sunday will see huge matchups in the South divisions with the Texans hosting the Jaguars and the Falcons hosting the Saints.

In the meantime, we’re back with straight-up picks for Week 12 of the regular season. We pick each game’s winner, and then slot the picks based on confidence levels — high, medium, low, and no. A game with three asterisks (***) after it indicates a game where I’m picking the betting underdog to get the win.

Last week was a solid week for me. I was 11-3 in total with a 3-0 high confidence record, 4-1 at medium, 1-2 at low, and 3-0 at no confidence.

On to the picks!

High confidence

Cowboys over Commanders
49ers over Seahawks
Dolphins over Jets
Chiefs over Raiders

Medium confidence

Lions over Packers
Patriots over Giants
Titans over Panthers
Colts over Bucs
Eagles over Bills
Ravens over Chargers
Vikings over Bears

Low confidence

Rams over Cardinals***
Browns over Broncos***

No confidence

Saints over Falcons***
Texans over Jaguars***
Bengals over Steelers***