Green Bay Packers vs. Minnesota Vikings prediction, pick for NFL Week 10 on Sunday 11/15/26

Kirk Cousins returns, most gloriously to Lambeau with Justin Jefferson still waiting for somebody to throw him a catchable football. Minnesota traded for Cousins five days before this game, after Carson Wentz’s 81-yard, two-interception calamity against Buffalo made another week of patience difficult to stomach. Kevin O’Connell knows how to call a game for Cousins. Getting the Vikings into the end zone more often would be a fine place to resume the relationship: they’ve scored touchdowns on just 12.5% of their possessions. Below is my preview, prediction, and pick for this week’s NFL game between the Green Bay Packers and the Minnesota Vikings.

Here’s how I’ll play it. I’ll be pumping out these predictions for individual games all season, with plenty of coverage here on DraftKings Network. Follow my handle @dansby_edits for more betting plays.

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Packers vs. Vikings prediction, preview

Cousins threw 20 touchdowns for Las Vegas before the trade, so Jefferson has reason to anticipate a livelier afternoon. O’Connell still has to reconstruct the passing game without T.J. Hockenson and Jauan Jennings, with Jordan Addison questionable because of his thumb. Minnesota’s runners have succeeded on only 31.8% of carries. Familiarity with the playbook helps; repeatedly asking Cousins to rescue third-and-long would squander much of it.

Across the ball, Brian Flores gets another crack at Green Bay’s interior protection. Center Sean Rhyan is out, Kevin Zeitler is questionable, and John Williams may again have to sort through Flores’ rushers before snapping the ball. Aaron Banks has no game designation. The Packers should be better equipped than they were when Jacob Monk and Donovan Jennings made their first starts in September, though that depends partly on Zeitler. A late strip-sack and interception helped Minnesota stretch that game into a 39–22 rout. At home, Jordan Love can at least communicate without shouting over the Minneapolis crowd.

I’d make Flores think hard before sending the fifth man. Love has thrown for an NFL-leading 967 yards and ten touchdowns against the blitz, repeatedly finding receivers where the extra rusher used to be. Seven of his completions in the opener traveled for at least 20 yards; Minnesota has conceded nine in its seven games since. Christian Watson and Matthew Golden have combined for 1,662 receiving yards and 12 touchdowns. They can punish another failed pressure call quickly.

Vikings vs. Packers pick, best bet

JFlores must manage those risks without Blake Cashman, while Joshua Metellus remains questionable. Josh Jacobs is out for Green Bay, however, and Chris Brooks’ Saturday activation leaves the distribution of carries unresolved. Love will have to finish plenty of the work himself. Minnesota has been outrageous inside its own 20, allowing touchdowns on just 26.3% of opponents’ visits. A few promising Packers possessions should end with the kicking unit jogging out.

Jefferson can absolutely spoil the afternoon, especially if Xavier McKinney or Javon Bullard cannot play. Both remain questionable. I expect Cousins to complete throws Minnesota has been missing, but Green Bay has already demonstrated how to attack Flores downfield. Love can win this through Watson and Golden while O’Connell is still piecing together his returning starter’s first game plan.

Best bet: Packers -2.5 (-120)

Projected score: Packers 24, Vikings 20.

Best Bet: Packers -2.5 (-120) vs. Vikings