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Prediction, pick for Stephen Thompson vs. Charles Radtke at UFC 334

Prediction, pick for Stephen Thompson vs. Charles Radtke at UFC 334

Published:

By: Cooper Albers

Stephen “Wonderboy” Thompson will make his final walk to the Octagon on Saturday night, taking on fellow welterweight veteran Charles Radtke at UFC 334: Gane vs. Hokit at Madison Square Garden in New York City. 

Thompson (17–9–1 MMA, 12–9–1 UFC) has dropped five of his last six fights — including three straight — and hasn’t fought since his split-decision loss to Gabriel Bonfim in July 2025. Radtke (12–5 MMA, 5–2 UFC) is coming off back-to-back wins, most recently scoring a dominant decision victory over Francisco Prado at UFC 327 in April. 

Thompson enters as a -155 moneyline favorite on DraftKings Sportsbook. Radtke is a +130 underdog, with the fight total set at O/U 2.5 rounds.

Stephen Thompson vs. Charles Radtke Fight Preview

Stephen Thompson

  • 17–9–1 MMA (12–9–1 UFC)
  • 8–2 (T)KO
  • 1–1 SUB

Stephen Thompson is hanging up the gloves on Saturday night, looking to punctuate his career with a victory at Madison Square Garden. It’ll be easier said than done; at 43, he’s the oldest fighter on the active roster. The former title challenger has also dropped five of his last six fights — two by stoppage — and has been out of action for 16 months. 

That said, all of Thompson’s losses during that stretch came against elite competition, including eventual welterweight champion Belal Muhammad and the undefeated Shavkat Rakhmonov. But for his retirement fight, “Wonderboy” draws a much friendlier — albeit still formidable — matchup against Charles Radtke. While Thompson has been vulnerable against grapplers in the past, he is characteristically hard to keep down. If he can thwart Radtke’s offensive wrestling, he can impose his signature, high-level karate striking one last time. 

Charles Radtke

  • 12–5 MMA (5–2 UFC)
  • 5–3 (T)KO
  • 3–0 SUB

Still searching for a statement win inside the Octagon, Charles Radtke heads to New York City to spoil the retirement fight of a UFC fan favorite. The 36-year-old veteran has bulldozed his last two opponents with his impressive wrestling. Over the last year, he submitted Daniel Frunza in the third round before scoring a 30–26 decision win over Francisco Prado, racking up significant control time in both bouts. 

“Chuck Buffalo” will likely attempt to follow a similar blueprint against a prolific striker in Stephen Thompson. However, Radtke has struggled to impose his will against strong competition. His last three wins have been against opponents coming off at least one loss, and he’s gotten knocked out by both Carlos Prates (June 2024) and Mike Malott (May 2025). While Thompson isn’t quite at that level anymore, he’ll mark another uphill battle for Radtke as he tries to prove himself in the UFC.

Stephen Thompson vs. Charles Radtke Pick, Best Bet

The biggest question heading into Stephen Thompson’s retirement fight is how his grappling will hold up at 43, after so much time away. If he can disrupt Charles Radtke’s offensive wrestling, “Wonderboy” can show off his clear advantage on the feet, bolstered by a considerable size advantage. Given Radtke’s compromised chin, a knockout victory could be within reach. But if Thompson’s grappling doesn’t endure, there’s a legitimate chance that Radtke ragdolls the Hall of Fame candidate like his last two opponents, potentially cinching a submission victory. Either way, it seems unlikely that Thompson’s curtain call goes the distance. 

Best Bet | Fight to go the Distance: NO (+110)

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Cooper is a Brooklyn-based writer and editor who joined DraftKings in September 2025. A recent graduate of Jay-Z’s Roc Nation School of Sports at Long Island University, he served as the chief sports editor of the campus newspaper and the lead sideline reporter for the men’s basketball team. His previous stops include amNewYork and the New York Post.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.

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