Eagles vs. Jaguars NFL Player Prop Bets for Week 5

The 2026 NFL London Games continue on Sunday with a Week 5 matchup between the Philadelphia Eagles and the Jacksonville Jaguars at Tottenham Hotspur Stadium, with kickoff set for 9:30 a.m. ET.

The Eagles (2–2, 2nd NFC East) have dropped back-to-back games and head to London without stars Saquon Barkley (hamstring) and DeVonta Smith (hamstring). The Jaguars (3–1, 1st AFC South) have won two in a row, coming out on top in 11 of their last 12 regular-season games since Week 11 of last year. 

Jacksonville is a 7.5-point favorite with -380 moneyline odds on DraftKings Sportsbook. Philadelphia is a +300 underdog, with the game total set at O/U 41.5 points. 

Let’s dive into the top player prop bets for Sunday’s clash between the Eagles and the Jaguars. 

Eagles vs. Jaguars NFL Player Prop Bets for Week 5

Bhayshul Tuten Anytime Touchdown (-105)

The Bhayshul Tuten breakout is looming. The second-year running back has seized control of Jacksonville’s backfield, handling 60 carries for 277 yards (4.6 YPC) and two touchdowns early on this season. Tuten is one of only five RBs to record at least 65 rush yards in every game so far, and he currently boasts the highest PFF rushing grade among qualified running backs (89.1). 

After having not one, but two touchdowns called back in the Jaguars’ Week 4 win over the Bengals, Tuten has a prime opportunity to punch one in across the pond against a struggling Philadelphia defense. The Eagles have allowed the NFL’s 10th-most rushing yards per game (122) and are tied for the second-most opponent rushing scores (7).

Dontayvion Wicks 50+ Receiving Yards (+111)

Dontayvion Wicks is one of the few Philadelphia pass-catchers not listed on the injury report for Week 5. The fourth-year receiver should step into a starring role for the Eagles, who head to London without Saquon Barkley, DeVonta Smith, and Hollywood Brown.

Wicks has flashed budding chemistry with Jalen Hurts in his first season with the Eagles, hauling in 12 of his 19 targets for 197 yards and a touchdown. He hit the ground running with 70+ receiving yards in both Weeks 1 and 2. Although he’s cooled off since, Wicks is positioned to step into a WR1 role in a matchup that should heavily favor the passing game. Often playing from ahead, the Jaguars have allowed the NFL’s second-most passing yards per game (280.3) and the fifth-most yards per reception (12.3) early on this year.