Track the most important injuries across the entire NFL Week 1 slate. This report covers all 16 games and is updated as teams release practice participation and game-status information throughout the week.
Official game status designations (Questionable, Doubtful, Out) will be added as teams release their final injury reports.
Patriots at Seahawks (Wednesday, 8:20 p.m. ET)
| Player | Pos | Team | Injury | Status |
|---|---|---|---|---|
| TreVeyon Henderson | RB | Patriots | Ankle | DNP |
| Ben Brown | C | Patriots | Knee | Out |
| Harold Landry III | LB | Patriots | Undisclosed | Out (PUP) |
| Zach Charbonnet | RB | Seahawks | Knee/ACL | Out (PUP) |
| Ty Okada | S | Seahawks | Hamstring | DNP |
| Nick Emmanwori | S | Seahawks | Ankle | LP |
New England Patriots
- TreVeyon Henderson, RB — Ankle: DNP at Monday’s (Sep. 7) practice. Has not participated all week.
- Ben Brown, C — Out: Knee; ruled out after missing all practices.
- Harold Landry III, LB — Out (PUP): Will miss at least the first four games.
Seattle Seahawks
- Zach Charbonnet, RB — Out (PUP): Rehabbing torn ACL; unavailable until at least Week 5. Emanuel Wilson expected to handle early-down work.
- Ty Okada, S — Hamstring: DNP on Monday (Sep. 7).
- Nick Emmanwori, S — Ankle: Limited at Monday’s (Sep. 7) practice but coach Macdonald said he “did the most work he has yet.” Both starting safeties are dealing with injuries ahead of the opener.
49ers at Rams (Thursday, 8:35 p.m. ET, Melbourne)
| Player | Pos | Team | Injury | Status |
|---|---|---|---|---|
| Christian McCaffrey | RB | 49ers | Undisclosed | — |
| Nick Bosa | DE | 49ers | Knee | — |
| George Kittle | TE | 49ers | Achilles | — |
| Mike Evans | WR | 49ers | Adductor | — |
| Ricky Pearsall | WR | 49ers | PCL | Out (IR) |
| Christian Kirk | WR | 49ers | Calf | Out (IR) |
| Myles Garrett | DE | Rams | Knee | — |
| Puka Nacua | WR | Rams | Core | — |
| Alaric Jackson | OT | Rams | Blood clot | — |
San Francisco 49ers
- Christian McCaffrey, RB — Undisclosed: In full uniform at Tuesday’s (Sep. 8) Melbourne practice. Expected to play.
- Nick Bosa, DE — Knee: Confirmed to play Thursday per the coaching staff.
- George Kittle, TE — Achilles: Full uniform at Tuesday’s (Sep. 8) Melbourne practice. Expected to play.
- Mike Evans, WR — Adductor: Full uniform at Monday’s (Sep. 7) open practice in Melbourne. On track for his 49ers regular-season debut.
- Ricky Pearsall, WR — Out (IR, Season-Ending): Done for the year after PCL surgery.
- Christian Kirk, WR — Out (IR): Calf; designation to return. Unavailable until at least Week 5.
Los Angeles Rams
- Myles Garrett, DE — Knee: Coach McVay said he will practice. Expected to play in his Rams debut Thursday.
- Puka Nacua, WR — Core: McVay expects him to play Thursday.
- Alaric Jackson, OT — Blood clot: Missed practice for blood clot management. Requires continued monitoring.
Bears at Panthers (Sunday, 1:00 p.m. ET)
| Player | Pos | Team | Injury | Status |
|---|---|---|---|---|
| Rome Odunze | WR | Bears | Leg | Questionable |
| Luther Burden III | WR | Bears | Groin | — |
| D’Andre Swift | RB | Bears | Abdomen | — |
| Kyler Gordon | CB | Bears | Calf | Out (PUP) |
| Ikem Ekwonu | OT | Panthers | Knee | Out (PUP) |
| Taylor Moton | OT | Panthers | NFI | Out |
| Derrick Brown | DT | Panthers | Undisclosed | — |
| Chuba Hubbard | RB | Panthers | Hamstring | — |
Chicago Bears
- Rome Odunze, WR — Questionable: Leg; DNP on Monday (Sep. 7).
- Luther Burden III, WR — Groin: Coach Ben Johnson said he will practice Tuesday (Sep. 8).
- D’Andre Swift, RB — Abdomen: Returned to practice Monday (Sep. 7).
- Kyler Gordon, CB — Out (PUP): Calf; will miss at least the first four games. Jaylon Johnson (arm) is also dealing with an injury, leaving Chicago’s cornerback room thin.
Carolina Panthers
- Ikem Ekwonu, OT — Out (PUP): Knee; unavailable until at least Week 5.
- Taylor Moton, OT — Out (NFI): Carolina is without both starting tackles to open the season.
- Derrick Brown, DT — Undisclosed: Practice participation this week will determine availability.
- Chuba Hubbard, RB — Hamstring: Returned to practice Tuesday (Sep. 8).
Ravens at Colts (Sunday, 1:00 p.m. ET)
| Player | Pos | Team | Injury | Status |
|---|---|---|---|---|
| Zay Flowers | WR | Ravens | Lower body | — |
| Nnamdi Madubuike | DT | Ravens | Neck | — |
| Tyler Warren | TE | Colts | Adductor | — |
| Charvarius Ward | CB | Colts | Back | — |
Baltimore Ravens
- Zay Flowers, WR — Lower body: Was practicing as of Thursday (Sep. 3). Expected to play.
- Nnamdi Madubuike, DT — Neck: Was not placed on IR. Expected to be available.
Indianapolis Colts
- Tyler Warren, TE — Adductor: Spotted participating in Tuesday’s (Sep. 8) practice.
- Charvarius Ward, CB — Back: Doing individual drills Tuesday (Sep. 8). Not yet cleared for full team activities.
Falcons at Steelers (Sunday, 1:00 p.m. ET)
| Player | Pos | Team | Injury | Status |
|---|---|---|---|---|
| Michael Penix Jr. | QB | Falcons | Knee | Out |
| DK Metcalf | WR | Steelers | Undisclosed | — |
| Jalen Ramsey | CB | Steelers | Knee | — |
| Michael Pittman Jr. | WR | Steelers | Hamstring | — |
Atlanta Falcons
- Michael Penix Jr., QB — Out: Knee; inactive for the opener. Tua Tagovailoa named the starter.
Pittsburgh Steelers
- DK Metcalf, WR — Undisclosed: Expected to play.
- Jalen Ramsey, CB — Knee: Coach McCarthy indicated he will be activated from PUP.
- Michael Pittman Jr., WR — Hamstring: Expected to be available.
Browns at Jaguars (Sunday, 1:00 p.m. ET)
| Player | Pos | Team | Injury | Status |
|---|---|---|---|---|
| Dillon Gabriel | QB | Browns | Back | Out (IR) |
| Jakobi Meyers | WR | Jaguars | Hand | — |
Cleveland Browns
- Dillon Gabriel, QB — Out (IR): Back; will not return until at least mid-October. Coach Monken says the injury is “not considered serious,” but the IR placement forces Cleveland into an early-season quarterback adjustment.
Jacksonville Jaguars
- Jakobi Meyers, WR — Hand: Expected to practice Wednesday.
Buccaneers at Bengals (Sunday, 1:00 p.m. ET)
| Player | Pos | Team | Injury | Status |
|---|---|---|---|---|
| Emeka Egbuka | WR | Buccaneers | Toe | — |
| Ja’Marr Chase | WR | Bengals | Knee | — |
| Tee Higgins | WR | Bengals | Heel | — |
Tampa Bay Buccaneers
- Emeka Egbuka, WR — Toe: Was running routes at Monday’s (Sep. 7) practice.
Cincinnati Bengals
- Ja’Marr Chase, WR — Knee: In uniform for Monday’s (Sep. 7) practice. Expected to play.
- Tee Higgins, WR — Heel: Also in uniform Monday (Sep. 7). Both receivers on track for the opener.
Jets at Titans (Sunday, 1:00 p.m. ET)
| Player | Pos | Team | Injury | Status |
|---|---|---|---|---|
| Breece Hall | RB | Jets | Groin | — |
| Cedric Gray | LB | Titans | Concussion | — |
New York Jets
- Breece Hall, RB — Groin: “Expected to be ready for Week 1” per the team.
Tennessee Titans
- Cedric Gray, LB — Concussion: Entered concussion protocol after a UTV accident over the weekend. Must clear protocol before playing.
Saints at Lions (Sunday, 1:00 p.m. ET)
| Player | Pos | Team | Injury | Status |
|---|---|---|---|---|
| Alvin Kamara | RB | Saints | Knee | — |
| Brian Branch | S | Lions | Achilles | Out (PUP) |
| Kerby Joseph | S | Lions | Knee | Out (PUP) |
| Sam LaPorta | TE | Lions | Hip | — |
| Isiah Pacheco | RB | Lions | Back | Out (IR) |
New Orleans Saints
- Alvin Kamara, RB — Knee: Sidelined at Thursday’s (Sep. 3) practice. No update on whether he will return to practice this week.
Detroit Lions
- Brian Branch, S — Out (PUP): Achilles; will miss at least the first four games.
- Kerby Joseph, S — Out (PUP): Knee; also on PUP. Detroit opens 2026 without either starting safety.
- Sam LaPorta, TE — Hip: Did not play in any preseason game. Availability unclear.
- Isiah Pacheco, RB — Out (IR): Back; no clear return timetable per GM Holmes.
Bills at Texans (Sunday, 1:00 p.m. ET)
| Player | Pos | Team | Injury | Status |
|---|---|---|---|---|
| Khalil Shakir | WR | Bills | Undisclosed | — |
| Keon Coleman | WR | Bills | Foot | — |
| Tank Dell | WR | Texans | Knee | Out (IR) |
Buffalo Bills
- Khalil Shakir, WR — Undisclosed: “Optimism” he will be available per CBS.
- Keon Coleman, WR — Foot: Present at Tuesday’s (Sep. 8) practice.
Houston Texans
- Tank Dell, WR — Out (IR): Knee; will not return until at least Week 5.
Cardinals at Chargers (Sunday, 4:25 p.m. ET)
| Player | Pos | Team | Injury | Status |
|---|---|---|---|---|
| James Conner | RB | Cardinals | Foot | Out (IR) |
| Jeremiyah Love | RB | Cardinals | Ankle | — |
| Rashawn Slater | OT | Chargers | Undisclosed | — |
| Tyler Biadasz | C | Chargers | Knee | Out (IR) |
Arizona Cardinals
- James Conner, RB — Out (IR): Foot; designation to return. Combined with Trey Benson (knee, IR, season-ending), Arizona has lost its top two backs.
- Jeremiyah Love, RB — Ankle: Coach LaFleur is “optimistic” the No. 3 overall pick will play. With Conner and Benson on IR, Love is the only healthy option at the position.
Los Angeles Chargers
- Rashawn Slater, OT — Undisclosed: Limited in Saturday’s (Sep. 5) practice.
- Tyler Biadasz, C — Out (IR, Season-Ending): Knee; done for the year.
Packers at Vikings (Sunday, 4:25 p.m. ET)
| Player | Pos | Team | Injury | Status |
|---|---|---|---|---|
| Micah Parsons | DE | Packers | Knee | Out (PUP) |
| Josh Jacobs | RB | Packers | Personal | Out |
| Tucker Kraft | TE | Packers | Knee | — |
Green Bay Packers
- Micah Parsons, DE — Out (PUP): Knee; will miss at least the first four games. GM Gutekunst said he could return when first eligible in Week 5.
- Josh Jacobs, RB — Out (Personal): Unavailable due to a pending legal matter with a court date of September 10.
- Tucker Kraft, TE — Knee: Running without limitations at practice.
Minnesota Vikings
No major injuries currently affecting the Vikings’ lineup.
Dolphins at Raiders (Sunday, 4:25 p.m. ET)
| Player | Pos | Team | Injury | Status |
|---|---|---|---|---|
| Ashton Jeanty | RB | Raiders | Ankle | — |
Miami Dolphins
No major injuries currently affecting the Dolphins’ lineup.
Las Vegas Raiders
- Ashton Jeanty, RB — Ankle: Coach Kubiak expressed “optimism” he will be ready for Week 1.
Commanders at Eagles (Sunday, 4:25 p.m. ET)
| Player | Pos | Team | Injury | Status |
|---|---|---|---|---|
| Laremy Tunsil | OT | Commanders | Triceps | Out (IR) |
| Jer’Zhan Newton | DT | Commanders | Pectoral | Out (IR) |
| Odafe Oweh | LB | Commanders | Calf | — |
| Jonathan Greenard | LB | Eagles | Pectoral | — |
Washington Commanders
- Laremy Tunsil, OT — Out (IR): Triceps; will not return until approximately December.
- Jer’Zhan Newton, DT — Out (IR): Pectoral; out until approximately November.
- Odafe Oweh, LB — Calf: Participated in Monday’s (Sep. 7) walk-through.
Philadelphia Eagles
- Jonathan Greenard, LB — Pectoral: Activated off PUP on August 30.
Cowboys at Giants (Sunday, 8:20 p.m. ET, SNF)
| Player | Pos | Team | Injury | Status |
|---|---|---|---|---|
| Tyler Smith | G | Cowboys | Thumb | Out |
| Malik Nabers | WR | Giants | Knee | — |
| Tyrone Tracy Jr. | RB | Giants | Neck | — |
Dallas Cowboys
- Tyler Smith, G — Out: Thumb; scheduled for surgery and expected to miss four to six weeks.
New York Giants
- Malik Nabers, WR — Knee: Participated in individual and team drills at Wednesday’s (Sep. 2) practice. Expected to play.
- Tyrone Tracy Jr., RB — Neck: At practice Tuesday (Sep. 8) in a non-contact jersey.
Broncos at Chiefs (Monday, 8:15 p.m. ET, MNF)
| Player | Pos | Team | Injury | Status |
|---|---|---|---|---|
| Patrick Mahomes | QB | Chiefs | Knee | — |
| Marvin Mims Jr. | WR | Broncos | Foot | — |
| Jonathon Cooper | LB | Broncos | Personal | Out |
Denver Broncos
- Marvin Mims Jr., WR — Foot: Was not spotted at Monday’s (Sep. 7) practice.
- Jonathon Cooper, LB — Out (Personal): Facing legal charges, out indefinitely.
Kansas City Chiefs
- Patrick Mahomes, QB — Knee: “On track to start Week 1” per Ian Rapoport. Expected to play.
