The Week 6 Monday Night Football matchup sees the San Francisco 49ers host the Washington Commanders. One of the best ways to get in on the game is by playing DraftKings Pick6.
Here are my top Pick6 plays for the Week 6 Monday Night Football matchup.
San Francisco 49ers vs. Washington Commanders DraftKings Pick6 Picks for Monday Night Football
George Kittle More Than 0.5 Rushing + Receiving Touchdowns
George Kittle is having a solid season in the league’s best offense. He has gone for at least 70 receiving yards in three of his past four games. Kittle has also scored four touchdowns across his past four games. He should keep it rolling in a favorable matchup at home against the Commanders. Mike Evans might miss this game, which would only lead to more targets for Kittle, especially in the red zone. The 49ers have faced a tough slate of opposing defenses, but Kittle has dominated when facing easy opponents like the Cardinals and the Dolphins. He should dominate against Washington as well.
The Commanders rank 31st in the NFL in touchdowns allowed and 28th in receiving yards allowed to opposing tight ends. They are giving up 1.4 touchdowns per game to opposing tight ends. Washington ranks 25th in the league in defensive EPA/dropback and 27th in defensive dropback success rate. The 49ers lead the league in offensive EPA/dropback and should move it with ease through the air. That should lead to a score for Kittle.

Jayden Daniels More Than 38.5 Rushing Yards
Jacory Croskey-Merritt is out for this Monday Night Football game. The Commanders’ other two running backs, Rachaad White and Austin Ekeler, are also both banged up and questionable. That could have a big effect on the Commanders’ running game. It might be on Jayden Daniels to carry this offense on his own. In his return from injury last week, Daniels showed no signs of being scared to run the football. He ran it a season-high nine times for 103 yards and two touchdowns against the Giants. Daniels has now rushed for 172 yards over his past two games. He should run for at least 39 yards in this game. The Commanders are likely to be in a trailing game state against the 49ers, which means Daniels will be dropping back and trying to make plays for most of this game. That should lead to plenty of scramble opportunities, which should get Daniels over this number.

Brock Purdy More Than 249.5 Passing Yards
Brock Purdy has been the best quarterback in the NFL so far this season. The 49ers are 5-0, and Purdy leads all eligible quarterbacks in passing touchdowns, QBR, success rate and EPA/dropback. He should keep it rolling in this favorable matchup against the Commanders. The extra day of preparation with this game on Monday night should only make the San Francisco offense more dangerous, especially because Washington ranks 25th in defensive EPA/dropback and 27th in dropback success rate. The 49ers have faced some really tough defenses like the Rams, Broncos and Seahawks. However, in the two matchups against favorable opponents, the Cardinals and the Dolphins, Purdy threw for 297 yards and 287 yards. He should hit those heights against the poor Commanders secondary as well.

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What is DraftKings Pick6?
Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of 2+ players and select whether you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.
How to Play
Create a Pick Set
Create a Pick Set by choosing 2+ players from the same sport and Pick Group (a set of picks available from a group of set competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you can not pick the same player twice, and you must pick players from at least two different teams.
Enter an Amount
Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.
Sweat Your Picks
When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.
Compete for Prizes
Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.
Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!