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MLB Best Bets Today: Top Expert Picks and Predictions for Friday 4/17/26

MLB Best Bets Today: Top Expert Picks and Predictions for Friday 4/17/26

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By: DK.Network.Editors

Looking for the best MLB picks today? DraftKings Network analysts share their top bets and predictions for Fridayโ€™s slate on DraftKings Sportsbook.


To see all DraftKings betting analysis, head over to the DraftKings Network sports betting picks page!


Check out the numerous MLB betting markets available on DraftKings Sportsbook!


Zach Thompson: Top Home Run Props

Picks below! Read Zach’s full betting analysis here: MLB Best Bets: Top Home Run Props for Friday 4/17/26

Samuel Basallo 1+ Home Run (+610)

Colson Montgomery 1+ Home Run (+397)

Daulton Varsho 1+ Home Run (+501)


Bryan Armetta: Top NRFI Bets

Picks below! Read Bryan’s full betting analysis here: Best NRFI Bets Today: No Run First Inning MLB Picks For Friday 4/17/26

Orioles vs. Guardians NRFI (-125)

Royals vs. Yankees NRFI (-125)

Tigers vs. Red Sox NRFI (-140)


Brendan O’Sullivan: Orioles vs. Guardians prediction, pick

Pick below! Read Brendan’s full betting analysis here: Baltimore Orioles vs. Cleveland Guardians prediction, pick for MLB on Friday 4/17/26

Best Bet: Over eight runs (-110)


Griffin Wong: Tigers at Red Sox prediction, pick

Picks below! Read Griffin’s full betting analysis here: Detroit Tigers at Boston Red Sox prediction, pick for Friday 4/17/26

Best Bet:ย Boston Red Sox Moneyline (-131)

Strong Lean: Ranger Suรกrez vs. Casey Mize โ€“ Most Strikeouts Thrown: Casey Mize (-131)


DraftKings promoters may sometimes play on personal accounts in the games that advice is offered on. Personal views on the games and strategies above do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. DraftKings promoters may also deploy different players and strategies than what is recommended above. DraftKings promoters do not have access to any non-public information.