Looking for the best MLB picks today? DraftKings Network analysts share their top bets and predictions for Wednesday’s slate on DraftKings Sportsbook.
To see all DraftKings betting analysis, head over to the DraftKings Network sports betting picks page!
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Garion Thorne: Top Home Run Props
Picks below! Read Garion’s full betting analysis here: MLB Best Bets: Top Home Run Props for Wednesday 4/8/26
Yordan Alvarez 1+ Home Run (+213)
Jordan Walker 1+ Home Run (+474)
Bryan Armetta: Top NRFI Props
Picks below! Read Bryan’s full betting analysis here: MLB Best Bets: Top NRFI props for Wednesday 4/8/26
Braves vs. Angels NRFI (-120)
Diamondbacks vs. Mets NRFI (-140)
Tigers vs. Twins NRFI (-145)
Brendan O’Sullivan: Brewers vs. Red Sox prediction, pick
Pick below! Read Brendan’s full betting analysis here: Milwaukee Brewers vs. Boston Red Sox prediction, pick for MLB on Wednesday 4/8/26
Milwaukee Brewers ML (+113)
Brendan O’Sullivan: Padres vs. Pirates prediction, pick
Pick below! Read Brendan’s full betting analysis here: San Diego Padres vs. Pittsburgh Pirates prediction, pick for MLB on Wednesday 4/8/26