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Best MLB Prop Bets Today (April 1, 2026) – Picks, Props & Odds

Best MLB Prop Bets Today (April 1, 2026) – Picks, Props & Odds

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By: Steve Buchanan

Looking for the best MLB prop bets today? We’ve got you covered with top picks and betting angles for April 1, 2026. This slate features several strong offensive matchups along with a few pitchers in tough spots, creating value across both team totals and player props. We’re backing the Mets in a favorable matchup against Matthew Liberatore, targeting Jackson Merrill against Adrian Houser’s struggles with lefties, and fading Zac Gallen against a Tigers lineup that continues to produce at a high level. Let’s get into the best MLB prop bets on the board.

Check out more MLB picks and prop bets throughout the season.

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Best MLB Prop Bets Today (April 1, 2026)

  • Best Team Total: New York Mets over 4.5 runs (+100) Matthew Liberatore in a poor matchup against a lineup that crushes left-handed pitchers
  • Best Hitting Prop: Jackson Merrill 2+ Total Bases (+109) Adrian Houser struggles against lefties puts Merrill in a great spot to produce
  • Best Pitcher Prop: Zac Gallen under 16.5 outs recorded (-108) Tough matchup for Gallen against a great hitting Tigers lineup

Let’s break down why these are some of my favorite MLB prop bets today.

MLB Prop Bets Breakdown (April 1, 2026)

Let’s break down the top MLB prop bets and picks for today. Click on each headline below to view the latest odds and bet these plays on DraftKings Sportsbook.

New York Mets Team Total Over 4.5 runs (+100) vs. St. Louis Cardinals

Monitor the weather here, but if this game plays, the Mets are in a strong spot. I do like the Mets to score at least five runs against the Cardinals and Matthew Liberatore. To his credit, Liberatore had a good start to open 2026, allowing just one run through five innings. However, he did allow seven hits and had a FIP of 6.20, so it easily could have been a lot worse. This Mets lineup is excellent against lefties and particularly the four-seam fastball. Dating back to last season, today’s expected lineup has a combined .379 wOBA with a .232 ISO against that pitch.

When Liberatore departs, he’ll give way to a bullpen that’s already been tagged for a 6.43 ERA with a 4.24 FIP and a 5.1 BB/9. They should clear this 4.5 total this afternoon if this game can be played.

Jackson Merrill 2+ Total Bases (+109) vs. San Francisco Giants

I like this spot a lot for Merrill going against Adrian Houser and the Giants. Houser will be making his first start of the season after throwing 13 innings during Spring Training. Houser is a contact pitcher who struggles against left-handed bats. Last season, he posted a .351 wOBA with a 4.86 FIP and eight of the 10 home runs he allowed against them. Houser mainly throws a sinker as his main pitch, and Merrill had a .354 wOBA with a .320 ISO against it last season. I like this spot for him, and all the lefties in the Padres lineup this afternoon.

Zac Gallen under 16.5 outs recorded (-108) vs. Detroit Tigers

I can’t quit this Tigers offense. They’ve been printing money for bettors who’ve been taking their overs during this first week of the season. I like them to keep the offense rolling this afternoon against the Diamondbacks starter Zac Gallen. Gallen had a tough matchup to start the season against the Dodgers and only went four innings in that one, allowing four runs and throwing 76 pitches. Today doesn’t get much easier against a Tigers team that crushes fastballs, which Gallen throws nearly 50% of the time. I have a hard time believing that Gallen will make it deep into this game, as he needs to record an out in the sixth inning for this bet to lose.

More MLB Betting Content & Picks

Check out more MLB betting content and player props throughout the season on DraftKings Network.

Good luck with your MLB prop bets today!

Steve has been with DraftKings for over 10 years, covering baseball and football from a sports betting and fantasy perspective. He’s written hundreds of articles that have helped readers research and make informative bets or fantasy lineups. During this time, Steve has also been featured on a number of national broadcasts, including MLB Network, ESPN, and NFL Network.
Disclaimer

All views expressed are my own. I am an employee of DraftKings and am ineligible to play in public DFS or DKSB contests.