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NFL Betting Cheat Sheet: Best Bets, Picks, Props for Bears at 49ers on Sunday Night Football

NFL Betting Cheat Sheet: Best Bets, Picks, Props for Bears at 49ers on Sunday Night Football

NFL Sports Betting Picks DraftKings Sportsbook Insights Rail

Published:

By: DK.Network.Editors

Every week, DraftKings Network analysts share their favorite NFL bets on DraftKings Sportsbook for each NFL game.

Below is a collection of the top NFL best bets for Week 17 Sunday Night Football between the Bears and 49ers.

To see all DraftKings betting analysis, head over to the DraftKings Network sports betting picks page!

Check out the numerous NFL betting markets available on DraftKings Sportsbook!

Sean Barnard: Bears at 49ers Best Prop Bets

Picks below! Read Sean’s full betting analysis here: NFL Best Bets: Bears at 49ers Best Prop Bets on Sunday Night Football 12/28/25

Caleb Williams Over 224.5 Passing Yards (-111)

D’Andre Swift Over 57.5 Rushing Yards (-115)

Brock Purdy to Record 3+ Passing Touchdowns (+175)

Ryan Wohl: San Francisco 49ers vs. Chicago Bears prediction, pick

Picks below! Read Ryan’s full betting analysis here: Chicago Bears vs. San Francisco 49ers prediction, pick for NFL Week 17 on Sunday 12/28/25

49ers -3 (-112) vs Bears

DK.Network.Editors
Disclaimer

DraftKings promoters may sometimes play on personal accounts in the games that advice is offered on. Personal views on the games and strategies above do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. DraftKings promoters may also deploy different players and strategies than what is recommended above. DraftKings promoters do not have access to any non-public information.