During the week, DraftKings Network analysts give their favorite fantasy football picks for the upcoming DFS Sunday Football slate on DraftKings.
Below is a collection of top DraftKings fantasy football plays for Week 16 of the 2025 NFL season.
To see all DraftKings DFS analysis, head over to the DraftKings Network Fantasy Advice page!
Set your DraftKings fantasy football lineups here: NFL $2.25M Fantasy Football Millionaire [$1M to 1st]
Stan Son: Week 16 NFL DFS Targets
QB
Joe Burrow, Cincinnati Bengals at Miami Dolphins ($6,500)
Jacoby Brissett, Arizona Cardinals vs. Atlanta Falcons ($5,300)
RB
De’Von Achane, Miami Dolphins vs. Cincinnati Bengals ($8,800)
Kenneth Gainwell, Pittsburgh Steelers at Detroit Lions ($5,100)
WR
Ja’Marr Chase, Cincinnati Bengals at Miami Dolphins ($8,600)
DK Metcalf, Pittsburgh Steelers at Detroit Lions ($5,400)
TE
Trey McBride, Arizona Cardinals vs. Atlanta Falcons ($7,600)
Darren Waller, Miami Dolphins vs. Cincinnati Bengals ($3,500)
Defense/Special Teams
Texans DST vs. Las Vegas Raiders ($4,000)
Vikings DST at New York Giants ($2,800)
Read Stan’s full analysis here: Fantasy Football Picks Today: Top DraftKings NFL DFS Targets, Values for Week 16
Geoff Ulrich: Week 16 High-Upside NFL DFS Plays
Game Stack: Atlanta Falcons vs. Arizona Cardinals
Kirk Cousins ($5,600) – Bijan Robinson ($8,700) – Michael Carter ($5,400) – Kyle Pitts ($5,000)
QB
Baker Mayfield ($5,700)
RB
Rico Dowdle ($6,300)
WR
DK Metcalf (5,400)
Chimere Dike ($4,200)
TE
Brenton Strange ($3,900)
Defense/Special Teams
Vikings ($2,800)
Read Geoff’s full analysis here: DraftKings Fantasy Football Tournament Picks: Top High-Upside DFS Targets for NFL Week 16
Bryan Armetta: Week 16 NFL DFS Values
RB Tyler Allgeier, Atlanta Falcons at ARI ($4,700)
WR Xavier Worthy, Kansas City Chiefs at TEN ($4,400)
TE Darren Waller, Miami Dolphins vs. CIN ($3,500)
Read Bryan’s full analysis here: Fantasy Football Value Picks: Top DraftKings NFL DFS Bargain Plays for Week 16 2025