Every week, DraftKings Network analysts share their favorite NFL bets on DraftKings Sportsbook for each NFL game.
Below is a collection of the top NFL best bets for Week 12 Thursday Night Football between the Texans and Bills!
To see all DraftKings betting analysis, head over to the DraftKings Network sports betting picks page!
Check out the numerous NFL betting markets available on DraftKings Sportsbook!
Garion Thorne: First Touchdown Scorer Prop Bets for Bills at Texans
Woody Marks First Touchdown Scorer (+700)
Gabriel Davis First Touchdown Scorer (+2200)
Read Garion’s full betting analysis here: First Touchdown Scorer Prop Bets for Bills at Texans on Thursday Night Football
Dan Johnson: Houston Texans vs. Buffalo Bills prediction, pick
Texans +6 (-110) vs. Bills
Read Dan’s full betting analysis here: Houston Texans vs. Buffalo Bills prediction, pick for NFL Week 12 on Thursday 11/20/25
Sean Barnard: Bills vs. Texans Best Prop Bets
Josh Allen Anytime Touchdown (-120)
Josh Allen Under 19.5 Completions (-123)
Woody Marks Over 62.5 Rushing Yards (-114)
Read Sean’s full betting analysis here: NFL Best Bets: Bills vs. Texans Best Prop Bets on Thursday Night Football