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NBA Best Bets Today: Top picks, predictions, expert analysis for Wednesday 10/22/25

NBA Best Bets Today: Top picks, predictions, expert analysis for Wednesday 10/22/25

Updated:

By: DK.Network.Editors

Each day, DraftKings Network analysts share their favorite NBA bets on DraftKings Sportsbook. Below is a collection of the top NBA best bets for Tuesday’s slate.


To see all DraftKings betting analysis, head over to the DraftKings Network sports betting picks page!


Check out the numerous NBA betting markets available on DraftKings Sportsbook!


Bryan Armetta: Player Prop Bets

Chris Boucher over 8.5 points (-113)

Bam Adebayo under 28.5 points + rebounds (-123)

Jaren Jackson Jr. over 8.5 assists + rebounds (+102)

See Bryan’s full analysis and best bets here: Best NBA player prop bets for Wednesday 10/22/25


Keagan Smith: NBA Pick/Prediction

Top pick: Under 227.5 points (-110)

See Keagan’s full analysis and best bets here: Cleveland Cavaliers vs. New York Knicks prediction, pick for Wednesday 10/22/25


Charlie Cummings: NBA Pick/Prediction

Best Bet: Charlotte Hornets -5.5

Best Bet: Raptors vs. Hawks Under 235.5 Total Points (-108)

Best Bet: Heat vs. Magic Under 217.5 Total Points (-108)

See Charlie’s full analysis and best bets here: Brooklyn Nets vs. Charlotte Hornets prediction, pick on Wednesday 10/22/25, Toronto Raptors vs. Atlanta Hawks prediction, pick on Wednesday 10/22/25, Miami Heat vs. Orlando Magic prediction, pick on Wednesday 10/22/25


Disclaimer

DraftKings promoters may sometimes play on personal accounts in the games that advice is offered on. Personal views on the games and strategies above do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. DraftKings promoters may also deploy different players and strategies than what is recommended above. DraftKings promoters do not have access to any non-public information.