Kentucky faces Oklahoma on Saturday 10/17/26 at 7:30pm ET. The Sooners are 7-point favorites at DraftKings Sportsbook with the total set at 43.5. Here’s my prediction and best bet for the matchup.
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| Spread | Oklahoma -7 |
| Moneyline | Oklahoma -238/Kentucky +195 |
| Total | 43.5 |
| Prediction | Kentucky 21 – Oklahoma 24 |
| Best Bet | Kentucky +7 |
Kentucky vs. Oklahoma prediction
These Kentucky Wildcats are riding high. Back-to-back weeks now Kentucky has won in overtime on a walk off two-point conversion by the same exact score — 35-34. It took a big comeback on the road at South Carolina two weeks ago, and then the Wildcats knocked off a top-10 team in LSU at home.
Kentucky is now 5-1, with three straight SEC wins as the underdog. The lone loss came to Alabama in a game the Wildcats led at home at halftime. The other win was a beatdown of Texas A&M at Kyle Field. Congrats to Kentucky win total backers — it was the most-bet win total over in the preseason at DraftKings, and over bettors cashed O4.5 in early October.
Normally, I wouldn’t look to back a team riding this kind of wave, and coming off a big overtime win with a field storm at home. However, Oklahoma is coming off an even bigger win — a field goal at the buzzer to knock over No. 1 Texas in the Red River Rivalry. That kind of creates a wash when it comes to the spot here, but if you made me pick, I’d say it’s more of a letdown for OU.
Credit John Mateer for taking care of the ball against a good Texas defense, but he still threw the ball for just 155 yards. Oklahoma generated 14 of its 27 points on defense and special teams, blocking a punt for a touchdown and getting a pick six off Arch Manning. Not to mention the eventual game winning kick came off a takeaway off Manning.
Kentucky’s defense won’t exactly give the Sooners the same type of test that they’ve seen in Michigan, Georgia and Texas. However, Will Stein is a terrific coach that can scheme up a good offensive game plan here. This will be strength on strength when Kentucky’s offense faces the Oklahoma defense, and weakness on weakness when the OU offense matches up with Kentucky’s defense.
I just can’t trust the Sooners to win with margin with this offense. I’m not calling for the Wildcats to win a fourth consecutive SEC game as the underdog, but I am calling for them to keep this one tight.
Kentucky vs. Oklahoma best bet
CFB Best Bet: Kentucky +7 (-112)
For all of my college football best bets this week, check out my CFB cheat sheet on DraftKings Network.
