Track the most important injuries across the entire NFL Week 2 slate. This report covers all 16 games and is updated as teams release practice participation and game-status information throughout the week.
Lions at Bills (Thursday, 8:15 p.m. ET, TNF)
Player
Pos
Team
Injury
Status
Isiah Pacheco
RB
Lions
Back
Out (IR)
Brian Branch
S
Lions
Achilles
Out (PUP)
Kerby Joseph
S
Lions
Knee
Out (PUP)
Detroit Lions
Isiah Pacheco, RB — Out (IR): Back; underwent surgery Monday. Expected to miss approximately 12 weeks, per Ian Rapoport of NFL Network. Jahmyr Gibbs handled the full backfield workload in Week 1’s overtime win over the Saints.
Brian Branch, S — Out (PUP): Achilles; will miss at least the first four games.
Kerby Joseph, S — Out (PUP): Knee; will miss at least the first four games. Detroit remains without both starting safeties.
Buffalo Bills
No major injuries currently affecting the Bills’ lineup.
Eagles at Titans (Sunday, 1:00 p.m. ET)
Player
Pos
Team
Injury
Status
Landon Dickerson
G
Eagles
Knee
Out (IR)
Jonathan Greenard
LB
Eagles
Pectoral
—
Cedric Gray
LB
Titans
Concussion
—
Philadelphia Eagles
Landon Dickerson, G — Out (IR): Knee; placed on injured reserve Monday. Drew Kendall or Tyler Steen expected to replace him on the interior.
Jonathan Greenard, LB — Pectoral: Was ruled out for Week 1. Week 2 practice status TBD.
Tennessee Titans
Cedric Gray, LB — Concussion: Was out for Week 1 after a UTV accident over Labor Day weekend. Coach Saleh said Monday that Gray is trending toward playing Week 2 but still needs to clear the concussion protocol.
Steelers at Patriots (Sunday, 1:00 p.m. ET)
Player
Pos
Team
Injury
Status
A.J. Brown
WR
Patriots
Ankle (High)
Out (IR)
TreVeyon Henderson
RB
Patriots
Ankle
—
Joey Porter Jr.
CB
Steelers
Back
—
DeShon Elliott
S
Steelers
Undisclosed
Out (IR)
Pittsburgh Steelers
Joey Porter Jr., CB — Back: Was inactive for Week 1 at Atlanta after limited practice participation all week. Week 2 status is TBD.
DeShon Elliott, S — Out (IR): Undisclosed; will miss at least the first four games.
New England Patriots
A.J. Brown, WR — Out (IR): Ankle (high); expected to miss approximately six weeks, per Ian Rapoport of NFL Network. Suffered the sprain during the Week 1 loss at Seattle.
TreVeyon Henderson, RB — Ankle: Coach Vrabel said Henderson will practice Monday. Was out for the Week 1 opener and has a chance to make his 2026 debut Sunday.
Vikings at Bears (Sunday, 1:00 p.m. ET)
Player
Pos
Team
Injury
Status
Kyler Murray
QB
Vikings
Concussion
—
Jordan Mason
RB
Vikings
Thumb
—
Kyler Gordon
CB
Bears
Calf
Out (PUP)
Minnesota Vikings
Kyler Murray, QB — Concussion: Entered the concussion protocol after taking a hit from two Packers defenders in the first quarter of Sunday’s win. Coach O’Connell said Monday that Murray will be evaluated day by day. Cam Ward finished the game.
Jordan Mason, RB — Thumb: Being further evaluated after experiencing soreness during Sunday’s win over Green Bay. Had a near-even snap split with Aaron Jones in Week 1.
Kyler Gordon, CB — Out (PUP): Calf; will miss at least the first four games. Away from the team, working with his own trainer.
Panthers at Falcons (Sunday, 1:00 p.m. ET)
Player
Pos
Team
Injury
Status
Tua Tagovailoa
QB
Falcons
Oblique
—
Michael Penix Jr.
QB
Falcons
Knee
—
Chris Lindstrom
G
Falcons
Concussion
—
Jalen Coker
WR
Panthers
Ankle
—
Ikem Ekwonu
OT
Panthers
Knee
Out (PUP)
Taylor Moton
OT
Panthers
NFI
Out (NFI)
Brady Christensen
G
Panthers
Hamstring
Out (IR)
Carolina Panthers
Jalen Coker, WR — Ankle: In a walking boot Monday after rolling his ankle in the first quarter at Chicago. Coker called the injury minor and expects to play Sunday. Led the Panthers in receiving in Week 1.
Ikem Ekwonu, OT — Out (PUP): Knee; unavailable until at least Week 5.
Taylor Moton, OT — Out (NFI): Reserve/non-football illness list.
Brady Christensen, G — Out (IR): Hamstring; will miss at least the first four games. Carolina remains without three starting offensive linemen.
Atlanta Falcons
Tua Tagovailoa, QB — Oblique: Was ruled out for Week 1 after straining his oblique in practice Sep. 10. Week 2 practice status TBD.
Michael Penix Jr., QB — Knee: Inactive for Week 1. Was targeting a Week 2 or Week 3 debut, per Ian Rapoport of NFL Network. Cooper Rush started the opener.
Chris Lindstrom, G — Concussion: Diagnosed during Sunday’s loss to Pittsburgh. Must clear the concussion protocol to be available this week.
Packers at Jets (Sunday, 1:00 p.m. ET)
Player
Pos
Team
Injury
Status
Josh Jacobs
RB
Packers
Personal
Out (Exempt)
Micah Parsons
DE
Packers
Knee
Out (PUP)
Aaron Banks
G
Packers
Knee
—
Omar Cooper Jr.
WR
Jets
Ankle
—
Minkah Fitzpatrick
S
Jets
Groin
—
Green Bay Packers
Josh Jacobs, RB — Out (Exempt): Commissioner’s Exempt List. Pleaded no contest Sep. 10 to misdemeanor battery charges. The NFL may count time on the list as time served if a suspension is issued, per Adam Schefter of ESPN.
Micah Parsons, DE — Out (PUP): Knee; will miss at least the first four games. GM Gutekunst said he could return when first eligible in Week 5.
Aaron Banks, G — Knee: Tendinitis; was unable to clear pregame warmups and missed Week 1 despite practicing in limited fashion all week. Week 2 status TBD.
New York Jets
Omar Cooper Jr., WR — Ankle: First-round pick exited Sunday’s win over the Titans in the first quarter with an ankle sprain after a 30-yard catch on the opening drive. X-rays negative; MRI pending.
Minkah Fitzpatrick, S — Groin: Left Sunday’s win over the Titans in the first half. No return timetable yet.
Saints at Ravens (Sunday, 1:00 p.m. ET)
Player
Pos
Team
Injury
Status
Alvin Kamara
RB
Saints
Knee (MCL)
—
Cameron Jordan
DE
Saints
Hamstring
—
Audric Estime
RB
Saints
Thigh
Out (IR)
Zay Flowers
WR
Ravens
Hamstring
—
Ja’Kobi Lane
WR
Ravens
Wrist (Fracture)
—
Nnamdi Madubuike
DL
Ravens
Neck
—
New Orleans Saints
Alvin Kamara, RB — Knee (MCL): Was inactive for Week 1 against Detroit. Was targeting a Week 2 debut at Baltimore. Practice participation this week will determine availability.
Cameron Jordan, DE — Hamstring: Was ruled out for Week 1 after limited participation Friday. Week 2 practice status TBD.
Audric Estime, RB — Out (IR): Thigh; placed on IR before Week 1. Unavailable until at least Week 5.
Baltimore Ravens
Zay Flowers, WR — Hamstring: Left Sunday’s win over the Colts with under six minutes remaining. Coach Minter said Monday that Flowers is day-to-day and the injury is not considered serious, per Sam Cohn of The Baltimore Sun.
Ja’Kobi Lane, WR — Wrist (Fracture): Fractured his wrist in his NFL debut Sunday. Will receive second and third opinions this week before a return timeline is set.
Nnamdi Madubuike, DL — Neck: Was ruled out for Week 1. Week 2 practice status is TBD.
Bengals at Texans (Sunday, 1:00 p.m. ET)
Player
Pos
Team
Injury
Status
Tank Dell
WR
Texans
Knee
Out (IR)
Braden Smith
OT
Texans
Foot
Out (IR)
Henry To’oTo’o
LB
Texans
Shoulder
—
Cincinnati Bengals
No major injuries currently affecting the Bengals’ lineup.
Houston Texans
Tank Dell, WR — Out (IR): Knee; will not return until at least Week 5.
Braden Smith, OT — Out (IR): Foot; placed on IR Sep. 8.
Henry To’oTo’o, LB — Shoulder: Injured in the fourth quarter of Sunday’s loss to Buffalo. Was in a sling postgame. Coach Ryans said Monday the team is still deciding whether To’oTo’o will go to IR.
Browns at Buccaneers (Sunday, 1:00 p.m. ET)
Player
Pos
Team
Injury
Status
Dillon Gabriel
QB
Browns
Back
Out (IR)
Dylan Sampson
RB
Browns
Knee
—
Teven Jenkins
G
Browns
Back
—
Jeremiah Owusu-Koramoah
LB
Browns
Undisclosed
—
Jalen McMillan
WR
Buccaneers
Knee
—
Cleveland Browns
Dillon Gabriel, QB — Out (IR): Back; will not return until at least mid-October.
Dylan Sampson, RB — Knee: Was on crutches after Sunday’s loss at Jacksonville. Coach Monken said Monday the team is still evaluating severity; more information expected Wednesday.
Teven Jenkins, G — Back: Was ruled out for Week 1 after missing practices late in the week. Week 2 practice status TBD.
Jeremiah Owusu-Koramoah, LB — Undisclosed: Was out for Week 1.
Tampa Bay Buccaneers
Jalen McMillan, WR — Knee: Was inactive for Week 1 against Cincinnati after limited practice participation all week. Week 2 status is TBD.
Jaguars at Broncos (Sunday, 4:05 p.m. ET)
Player
Pos
Team
Injury
Status
Brian Thomas Jr.
WR
Jaguars
Shoulder
—
Jonathon Cooper
LB
Broncos
Exempt List
Out (Exempt)
Jacksonville Jaguars
Brian Thomas Jr., WR — Shoulder: Briefly left Sunday’s win over the Browns before returning. Finished with three catches for 40 yards. Coach Coen said Monday that Thomas will be limited in practice this week but expects him to play Sunday.
Denver Broncos
Jonathon Cooper, LB — Out (Exempt): Commissioner’s Exempt List. Jury trial set for Nov. 10.
Raiders at Chargers (Sunday, 4:05 p.m. ET)
Player
Pos
Team
Injury
Status
Brock Bowers
TE
Raiders
Knee (Meniscus)
—
Ladd McConkey
WR
Chargers
Rib
—
KeAndre Lambert-Smith
WR
Chargers
Hamstring
—
Derius Davis
WR
Chargers
Undisclosed
—
Tyler Biadasz
C
Chargers
Knee
Out (IR, Season-Ending)
Las Vegas Raiders
Brock Bowers, TE — Knee (Meniscus): Missed Week 1 following a meniscus trim procedure on Sep. 9. Coach Kubiak labeled him day-to-day Monday. Originally expected to miss one to two games.
Los Angeles Chargers
Ladd McConkey, WR — Rib: Exited Sunday’s loss to Arizona in the third quarter. Coach Harbaugh labeled him day-to-day Monday and will monitor his progress throughout the week.
KeAndre Lambert-Smith, WR — Hamstring: Left Sunday’s game early. Expected to miss multiple weeks.
Derius Davis, WR — Undisclosed: Day-to-day with an injury suffered during Sunday’s loss to Arizona. Week 2 availability depends on practice participation.
Tyler Biadasz, C — Out (IR, Season-Ending): Knee; done for the year.
Seahawks at Cardinals (Sunday, 4:25 p.m. ET)
Player
Pos
Team
Injury
Status
Sam Darnold
QB
Seahawks
Hip
—
Zach Charbonnet
RB
Seahawks
Knee (ACL)
Out (PUP)
James Conner
RB
Cardinals
Foot
Out (IR)
Tip Reiman
TE
Cardinals
Ankle
Out (PUP)
Seattle Seahawks
Sam Darnold, QB — Hip: Suffered a “very unique” soft-tissue injury during the Week 1 win over New England. His hip joint is unaffected, and the issue is considered short-term, per Brady Henderson of ESPN. Drew Lock would start again if Darnold is unavailable.
Zach Charbonnet, RB — Out (PUP): Knee (ACL); rehabbing a torn ACL. Unavailable until at least Week 5.
Arizona Cardinals
James Conner, RB — Out (IR): Foot; complications from an injury that ended his 2025 season. Placed on IR with a designation to return.
Tip Reiman, TE — Out (PUP): Ankle; moved to the reserve/PUP list. Must miss at least the first four games.
Dolphins at 49ers (Sunday, 4:25 p.m. ET)
Player
Pos
Team
Injury
Status
Ricky Pearsall
WR
49ers
Knee (PCL)
Out (IR, Season-Ending)
Christian Kirk
WR
49ers
Calf
Out (IR)
De’Zhaun Stribling
WR
49ers
Ankle
—
Jake Tonges
TE
49ers
Knee
—
Miami Dolphins
No major injuries currently affecting the Dolphins’ lineup.
San Francisco 49ers
Ricky Pearsall, WR — Out (IR, Season-Ending): PCL surgery. Done for the year.
Christian Kirk, WR — Out (IR): Calf; designation to return. Unavailable until at least Week 5.
De’Zhaun Stribling, WR — Ankle: Second-round pick diagnosed with a deltoid sprain after going down in his NFL debut Thursday. Expected to miss at least one month, per Ian Rapoport of NFL Network.
Jake Tonges, TE — Knee: Hobbled off during Thursday’s win over the Rams and was ruled out. Coach Shanahan said the injury “does not look good.”
Commanders at Cowboys (Sunday, 4:25 p.m. ET)
Player
Pos
Team
Injury
Status
Tyler Smith
G
Cowboys
Thumb
Out (IR)
Malik Hooker
S
Cowboys
Forearm (Fracture)
—
DeMarvion Overshown
LB
Cowboys
Hamstring
—
Laremy Tunsil
OT
Commanders
Triceps
Out (IR)
Jer’Zhan Newton
DT
Commanders
Pectoral
Out (IR)
Frankie Luvu
LB
Commanders
Groin
—
Chig Okonkwo
TE
Commanders
Hamstring
—
Washington Commanders
Laremy Tunsil, OT — Out (IR): Triceps; will not return until approximately December.
Jer’Zhan Newton, DT — Out (IR): Pectoral; out until approximately November.
Frankie Luvu, LB — Groin: Did not return after halftime of Sunday’s loss at Philadelphia. Severity unclear.
Chig Okonkwo, TE — Hamstring: Exited Sunday’s game in the second half. Had two catches for 16 yards before departing.
Dallas Cowboys
Tyler Smith, G — Out (IR): Thumb; expected to miss four to six weeks. T.J. Bass fills in at guard.
Malik Hooker, S — Forearm (Fracture): Diagnosed Monday after leaving Sunday’s win at New York in the fourth quarter. Likely to miss at least two weeks, per Calvin Watkins of The Dallas Morning News.
DeMarvion Overshown, LB — Hamstring: Coach Schottenheimer said Monday that Overshown is expected to miss one to two weeks.
Colts at Chiefs (Sunday, 8:20 p.m. ET, SNF)
Player
Pos
Team
Injury
Status
Mansoor Delane
CB
Chiefs
Shoulder
—
Josh Simmons
OT
Chiefs
Back
—
Chamarri Conner
S
Chiefs
Knee
—
Alec Pierce
WR
Colts
Wrist
—
Indianapolis Colts
Alec Pierce, WR — Wrist: Banged up his wrist in Sunday’s loss at Baltimore. Coach Steichen said Monday that Pierce is “good right now.”
Kansas City Chiefs
Mansoor Delane, CB — Shoulder: First-round rookie was ruled out of Monday night’s game after intercepting Bo Nix on the Broncos’ opening possession. The injury may be a flare-up of an existing issue from OTAs.
Josh Simmons, OT — Back: Was out for Week 1. Week 2 practice status is TBD.
Chamarri Conner, S — Knee: Was out for Week 1. Week 2 practice status is TBD.
Giants at Rams (Monday, 8:15 p.m. ET, MNF)
Player
Pos
Team
Injury
Status
Myles Garrett
DE
Rams
Knee
Out (IR)
Kam Curl
S
Rams
Ankle
—
New York Giants
No major injuries currently affecting the Giants’ lineup.
Los Angeles Rams
Myles Garrett, DE — Out (IR): Knee; Coach McVay confirmed Monday that Garrett will undergo a knee scope and be placed on injured reserve. Will miss at least the next four games.
Kam Curl, S — Ankle: Dealing with ankle soreness after Thursday’s loss to San Francisco. May start the week as a limited participant.
