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Saquon Barkley best prop bet for Eagles at Bills on Sunday 12/28/25

Saquon Barkley best prop bet for Eagles at Bills on Sunday 12/28/25

Buffalo Bills Sports Betting Picks NFL DraftKings Sportsbook Insights

Published:

By: Alex Hunter

The Eagles are visiting the Bills on Sunday. On DraftKings Sportsbook, Buffalo is favored by three points and this game carries a total of 44.5 points.

Below, I have featured my favorite Saquon Barkley prop to consider from this contest.

Best Saquon Barkley Prop Bets on DraftKings Sportsbook

Saquon Barkley O 84.5 Rushing Yards (-112)

Barkley enters this matchup vs. the Bills in great form. In his last three starts, Barkley has rushed for 122, 78 and 132 yards. Over this time, the back is averaging 5.3 YPC and he is seeing huge volume, averaging 21 carries per game.

The Eagles are running the ball at the fourth-highest rate in the NFL during this stretch (53.5%) and they should continue to feed Barkley vs. the Bills, given Buffalo is much easier to attack on the ground than through the air.

This season, the Bills are allowing the sixth-fewest yards per pass (6.0), but the second-most yards per rush (5.4). Barkley should flourish in this spot and clear 84.5 rushing yards.

Alex Hunter
Alex Hunter is an avid DFS player and sports handicapper, who has been a proud member of the DraftKings Network team since 2020. He is a data-driven analyst, who earned his bachelor’s degree in communications at Worcester State University and has been in the sports content business for nearly a decade, covering the NBA, NFL and PGA TOUR. Alex is a diehard Boston Celtics fan, who loves to be on the golf course when he isn’t grinding lineups or producing content. For all of Alex’s work or if you need any lineup advice, be sure to follow him @Hunta512 on X.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is Hunta512) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.