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Fantasy Basketball Picks: Top DraftKings NBA DFS Targets, Values for Wednesday 12/17/25

Fantasy Basketball Picks: Top DraftKings NBA DFS Targets, Values for Wednesday 12/17/25

Updated:

By: Alex Hunter

Following the NBA Cup final won by the Knicks on Tuesday, the NBA season continues Wednesday with a two-game slate. DraftKings continues to offer huge contests for DFS players, and below, I break down some of my favorite NBA DFS options at each position for Wednesday’s NBA action.


Set your DraftKings fantasy basketball lineups here: NBA $300K Fadeaway [$100K to 1st]


Guard

Stud

Donovan Mitchell, Cleveland Cavaliers at Chicago Bulls, $9,800

While Mitchell disappointed with Evan Mobley (calf) inactive this past Sunday vs. the Hornets, finishing with just 35.5 FPTS, we have to go right back to the well tonight. Mobley remains sidelined and with the big man off the court this season, Mitchell’s usage increases 6.8 percentage points to 40.4% and he generates a team-high 1.5 FPTS per minute.

The Bulls are an elite matchup, ranking second in pace and 24th in defensive rating, and the Cavaliers carry the highest implied team total on the slate at 123.5 points on DraftKings Sportsbook. Mitchell is a strong investment for over 50 FPTS in this spot and he is the No.1 option for this two-game slate.

Other Options: Josh Giddey ($9,200)

Value

Darius Garland, Cleveland Cavaliers at Chicago Bulls, $6,800

Garland also benefits greatly with Mobley out and rostering Mitchell and Garland together in this great matchup vs. the Bulls is smart for this short slate.

Garland scored a season-best 45.5 FPTS across 39 minutes with Mobley inactive Sunday vs. the Hornets and with the forward off the floor this season, Garland’s usage skyrockets a team-high 10.7 percentage points to 36.2% and he scores 1.1 FPTS per minute.

Other Options: Cedric Coward ($6,100), Lonzo Ball ($4,600)


Forward

Stud

Julius Randle, Minnesota Timberwolves vs. Memphis Grizzlies, $9,000

Randle is a solid option no matter what, that would become a necessity if Anthony Edwards (questionable, foot) remains out. The Timberwolves are hosting the Grizzlies who will be without Zach Edey (out, ankle), which makes this an awesome matchup. Edey has been one of the most impactful defenders in the NBA this season, as with him off the floor, Memphis’ defensive rating is a huge 23.8 points worse at 118.3.

Randle should thrive in this spot and his upside will increase if Edwards sits. This season, Randle is scoring 43.3 FPTS per game with a 27.3% usage rate and with Edwards inactive, those numbers increase to 46.5 FPTS per game and a 28.9% usage rate for Randle.

Value

Jaylen Wells, Memphis Grizzlies at Minnesota Timberwolves, $5,200

Wells starts at small forward for the Grizzlies and the team has been relying on him heavily recently. In Memphis’ last 10 games, Wells is providing 27 FPTS in 29.7 minutes per game, which ranks second only to Jackson Jr. during this time.

Wells is scoring 0.8 FPTS per minute with an 18% usage rate while shooting 45% from the field this season. The Timberwolves aren’t a great matchup, ranking 10th in defensive rating, but Wells is the best forward value this short slate has to offer.

Other Options: Santi Aldama ($6,400), Jaylon Tyson ($6,200)


Center

Stud

Jaren Jackson Jr., Memphis Grizzlies at Minnesota Timberwolves, $7,700

Jackson Jr. is the only center who is priced above $7,000 tonight and he is the highest projected player at the position, but spending up at center isn’t a wise move for this short slate and Jackson Jr. will only warrant GPP consideration if Morant sits.

With Morant and Edey off the floor this season, Jackson Jr.’s usage rises 5.1 percentage points to 30% and he produces 1.13 FPTS per minute.

Value

Dean Wade, Cleveland Cavaliers at Chicago Bulls, $4,100

With Mobley out this past Sunday vs. the Hornets, Wade moved into the Cavaliers’ starting lineup and had one of his best games of the season, posting 30.5 FPTS in a season-high 31.3 minutes.

Cleveland did lose this game, so it’s no guarantee Wade will continue to start, but if he does, the veteran will be a viable punt play in this prime spot vs. the Bulls. This season, Wade is generating 0.7 FPTS per minute and he is averaging 18.3 FPTS per game when he has cracked the 20-minute mark (18 games).

Other Options: Jarrett Allen ($6,000), Patrick Williams ($3,500)

Alex Hunter is an avid DFS player and sports handicapper, who has been a proud member of the DraftKings Network team since 2020. He is a data-driven analyst, who earned his bachelor’s degree in communications at Worcester State University and has been in the sports content business for nearly a decade, covering the NBA, NFL and PGA TOUR. Alex is a diehard Boston Celtics fan, who loves to be on the golf course when he isn’t grinding lineups or producing content. For all of Alex’s work or if you need any lineup advice, be sure to follow him @Hunta512 on X.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is Hunta512) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.