Every week, DraftKings Network analysts share their favorite NFL bets on DraftKings Sportsbook for each NFL game.
Below is a collection of the top NFL best bets for the Week 13 NFL Sunday slate.
To see all DraftKings betting analysis, head over to the DraftKings Network sports betting picks page!
Check out the numerous NFL betting markets available on DraftKings Sportsbook!
Ryan Wohl: Best NFL Prop Bets for Texans vs. Colts
Jonathan Taylor Over 109.5 Rushing + Receiving Yards (-113)
Michael Pittman Over 4.5 Receptions (-105)
Daniel Jones Over 226.5 Passing Yards (-113)
Read Ryan’s full betting analysis here: Best NFL Prop Bets for Texans vs. Colts on Sunday 11/30/25
Brendan O’Sullivan: Jaguars vs. Titans Best Prop Bets
Cam Ward over 20.5 completions (+100)
Travis Etienne Jr. over 62.5 rushing yards (-115)
Tony Pollard under 38.5 rushing yards (-111)
Read Brendan’s full betting analysis here: NFL Best Bets: Jaguars vs. Titans Best Prop Bets for Week 13
Keagan Smith: Minnesota Vikings vs. Seattle Seahawks prediction, pick
MIN Vikings under 14.5 points (-118)
Read Keagan’s full betting analysis here: Minnesota Vikings vs. Seattle Seahawks prediction, pick for NFL Week 13 on Sunday 11/30/25
Dan Johnson: Pittsburgh Steelers vs. Buffalo Bills prediction, pick
Bills -3 (-110) at Steelers
Read Dan’s full betting analysis here: Pittsburgh Steelers vs. Buffalo Bills prediction, pick for NFL Week 13 on Sunday 11/30/25