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Los Angeles Rams vs. Seattle Seahawks prediction, pick for NFL Week 11 on Sunday 11/16/25

Los Angeles Rams vs. Seattle Seahawks prediction, pick for NFL Week 11 on Sunday 11/16/25

Updated:

By: Dan Johnson

SoFi will glow under midnight blue while Los Angeles tries to defend home turf and first place simultaneously. Seattle arrives 7-2 with four straight wins and the league’s best points-per-play mark at 0.535, a fireworks profile that tempts the over. The Rams also sit 7-2 and recently dropped 42 on San Francisco, part of a three-game stretch with 111 points and elite offensive EPA. Yet both defenses live in rare air, top-five in defensive EPA per play, and the DVOA crowd calls this a one-versus-two showdown. With Rams -3 and a total at 48.5, I still lean hardest toward the under. Below is my prediction for NFL Week 11’s game between the the Los Angeles Rams and the Seattle Seahawks.

Here’s how I’ll play it. I’ll be pumping out these predictions for individual games all season, with plenty of coverage here on DraftKings Network. Follow my handle @dansby_edits for more betting plays.

Rams vs. Seahawks prediction, preview

Seattle’s offense is real, not noise. They sit top-12 in EPA per play, seventh in success rate, built on shifts, motion, and play action that bend rules without living on gadgetry. They rank third in scoring and first in points per play, so the efficiency has cashed. The Rams defense, though, is designed to cool this exact profile. They allow –0.09 EPA per snap, fourth in the league, with a 42.8% success rate allowed, –0.07 against the pass and –0.11 against the run. Their front sits top-five in EPA per rush at –0.158, colliding with a Seahawks backfield where Kenneth Walker and Zach Charbonnet split carries and Charbonnet owns ten inside-the-five rushes and six touchdowns. You can move the ball, but hammering in drive after drive on the ground into that front is a tougher assignment than Seattle’s point totals suggest.

The other side is strength on strength. The Rams offense owns 0.10 EPA per play with a 49.6% success rate, driven by 0.24 EPA per dropback and a 66.9% pass rate. Since Week 7 they have stacked 111 points in three games and dropped a 0.379 EPA per play, 401 yards, and six yards per snap on San Francisco. A huge chunk came from 13 personnel: nearly 45% usage, 6.7 yards per play, a 63.3% success rate, and four touchdowns out of that grouping, a classic McVay counter when defenses lean light. Seattle’s defense sits right beside them in the tables. They allow –0.06 EPA per play, fifth in the league, with a 41.9% success rate allowed, –0.15 against the pass and essentially neutral against the run. They are fourth in defensive EPA, have surrendered only two explosive runs all season, and their zone coverage is top-five in yards per coverage target and explosive pass rate allowed. That shell keeps the lid on even when Puka Nacua and Davante Adams win off the line.

The individual matchups still crackle. Against zone, Puka has 48 catches for 544 yards on 162 routes with a 34.6% target rate and 0.67 points per route, third among receivers. Davante carries 29 catches for 435 yards on 188 zone routes with a 26.1% target rate and 0.48 points per route, 14th in that efficiency cluster. They are engineered to beat zone, and Seattle plays plenty of it, but the Seahawks’ discipline pushes those wins underneath the umbrella more than over the top. On the ground, Kyren Williams owns 59.6% of Rams running-back carries on 146 attempts, with Blake Corum now in an early 50/50 split by usage and quietly siphoning red-zone work. Corum has 13 touches in three straight games and six red-zone carries across that stretch. The Rams’ red-zone offense, stuffed with tight-end roles and Kyren’s 27 red-zone carries and eight rushing touchdowns, runs into a Seahawks red-zone defense that ranks near the top in success suppression. That is the texture of field goals, not a parade of easy sevens.

Sam Darnold’s history with this pass rush adds another layer. Last January, as Minnesota’s starter, he was sacked nine times in a 27-9 wild-card loss to these Rams, tying a playoff record and losing 82 yards in the process. Next Gen tracking had him pressured on 52% of his dropbacks with 26 total pressures, many created by coverage as much as rush. Earlier that season, he faced them in the regular season and still took three sacks despite throwing for 240 yards and two scores. Now he gets a different ecosystem in Seattle, with Klint Kubiak’s offense leaning heavier under center, play-action, and defined reads after a shotgun-heavy 2024 experiment. That should protect him better, but it also means the Rams have a very recent blueprint on his internal clock and favorite bailout spots. In an environment this familiar and this physical, sacks and throwaways become drive-killers that quietly help an under.

Seahawks vs. Rams pick, best bet

Seattle is 6-3 to the over. Both teams sit top-six in points per play and top-five in scoring defense, a weird but potent cocktail where short fields can flip a seemingly modest 48.5 into a game that lands in the low fifties. The Rams’ surge—111 points in three—proves McVay can still script stretches where every first-and-ten feels on schedule. That 13 personnel package against lighter boxes can pop explosives if Seattle misses fits. Charbonnet’s goal-line dominance and the Rams allowing the 12th-most receiving yards to opposing receivers keep the Seahawks ceiling live; Jaxon Smith-Njigba is already over 1,000 yards in nine games, and this passing game can punish a single missed tackle or bad leverage snap.

I still land on the under because the defenses’ best traits sit directly on top of the offenses’ favorite answers. Both fronts win early downs and live in negative EPA territory. Both secondaries are built to strangle explosives, not invite them, and this rivalry has enough film on both sides that neither staff should get ambushed by core concepts. The Rams’ red-zone defense has faced 99 plays, allowing only 29.4% successful passes and 25.8% successful runs, both top-seven marks. Seattle’s red-zone group sits third in limiting offensive success, forcing quarterbacks to feather throws into tight windows rather than hitting wide-open crossers. The Seahawks defense also bleeds underneath catches to running backs and tight ends—fifth-most receiving yards to both groups and the most tight end receptions—but that distribution feeds yardage and clock more than it feeds an explosive scoring environment. Sustained drives, compressed red zones, and two detail-obsessed staffs tilt this toward a bruising, possession-by-possession game where every three points matters.

The script I see keeps both teams moving while the scoreboard trails the yardage between the twenties. Seattle should lean on play action and motion, running just enough with Walker and Charbonnet to keep the Rams honest, then letting Smith-Njigba and the tight ends bend those zones in the seams. Los Angeles should lean back into 13 personnel, using tight ends and Corum to distort fronts, feeding Puka and Davante on in-breakers and option routes instead of constant vertical shots. Third downs become money downs, not explosion downs, and both defenses are built to win their share when the stadium tightens. Under midnight lights, with two top-five defenses and playoff leverage humming in the building, I trust the resistance more than I trust fireworks.

Under 48.5 is the bet, with a projected 23–20 Rams win that looks and feels like January football even with Thanksgiving still on deck.

Best bet: Rams vs. Seahawks u48.5 points (-110)

Tail it with me in the DKN Betting Group here!

For a prop lean, let’s take Kyren Williams to hit paydirt (-115). I don’t mind that price range after 659 rushing yards on 146 carries and eight total scores, with 22 catches for 177 yards and three more touchdowns. He owns 59.6% of Rams running-back carries and 27 red-zone rushes, converting eight of those into touchdowns while handling most of the high-leverage work. Seattle’s run defense is excellent per carry but faces plenty of plays and has allowed generous receiving and red-zone volume to backs. Williams cashing a single score inside the 10 fits neatly alongside a game that still finishes under the total, especially if the Seahawks force McVay to lean on his most trusted finisher rather than chase explosives all night.

Best prop lean: Kyren Williams to score a touchdown (-115)

Tail it with me in the DKN Betting Group here!

Dan Johnson has been an editor, writer, and analyst for DraftKings and DraftKings Network since 2024. He’s previously held editorial posts at The Paris Review, Macmillan Publishers, Bedford/St. Martin’s Press, ASSIGNMENT Magazine, and FantasySixPack. You can find his various editorial work & writing (sports-related and non-) at all of the above.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is thegreatdansby9) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.