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DraftKings NFL Pick6 Fantasy Football Picks: Top Plays and Projections for Week 10 on Sunday 11/9/25

DraftKings NFL Pick6 Fantasy Football Picks: Top Plays and Projections for Week 10 on Sunday 11/9/25

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By: DK.Network.Editors

DraftKings Network analysts use their projections to help you build your DraftKings Pick6 pick sets for Week 10 of the 2025 NFL season.


NY Giants at CHI Bears

Caleb Williams Passing Touchdowns  

  • Pick6 Listed Stat Projection: 1.5
  • DraftKings Network projection: 54% likely to have LESS than 1.5 Passing Touchdowns

Pick Set Play: LESS


BUF Bills at MIA Dolphins

James Cook Rushing Yards

  • Pick6 Listed Stat Projection: 86.5
  • DraftKings Network projection: 54% likely to have MORE than 86.5 Rushing Yards

Pick Set Play: MORE


BAL Ravens at MIN Vikings

Zay Flowers Receptions

  • Pick6 Listed Stat Projection: 5.5
  • DraftKings Network projection: 55% likely to have LESS than 5.5 Receptions

Pick Set Play: LESS


NE Patriots at TB Buccaneers

Emeka Egbuka Receiving Yards

  • Pick6 Listed Stat Projection: 69.5
  • DraftKings Network projection: 54% likely to have MORE than 69.5 Receiving Yards

Pick Set Play: MORE


What is DraftKings Pick6?

Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of 2+ players and select whether or not you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.

How to Play

Create a Pick Set

Create a Pick Set by choosing 2+ players from the same sport and Pick Group (a set of picks available from a group of set competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you can not pick the same player twice and you must pick players from at least two different teams.

Enter an Amount

Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.

Sweat Your Picks

When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.

Compete for Prizes

Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.


Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!


Gambling Problem? Call 1-800-GAMBLER. Must be at least 18 years or older. Higher age limits may apply in some states. Eligibility restrictions apply. Valid only in states where DraftKings Pick6 operates. Void where prohibited. For entertainment purposes only. Winning a contest on DraftKings depends on knowledge and exercise of skill. See terms at pick6.draftkings.com.


Disclaimer

DraftKings promoters may sometimes play on personal accounts in the games that advice is offered on. Personal views on the games and strategies above do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. DraftKings promoters may also deploy different players and strategies than what is recommended above. DraftKings promoters do not have access to any non-public information.