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Top DraftKings Pick6 NFL Picks: Most Popular Plays from Week 10

Top DraftKings Pick6 NFL Picks: Most Popular Plays from Week 10

DraftKings Fantasy Advice Pick6 NFL

Published:

By: Sam Connon

With another Sunday in the rear-view mirror, another DraftKings Pick6 contest has come and gone. Whether the NFL players themselves came in above or below their projected lines, there were winners on all sides.

Every week, we’ll be taking a look at which players and plays helped the most NFL Pick6 lineups. After customers reaped the rewards of Jonathan Taylor’s career day over in Germany, Jahmyr Gibbs returned to form and Kyren Williams stayed hot during the main slate. Sunday Night Football once again drew the most eyeballs, with a handful of Chargers and Steelers propping up Pick6 lineups to round out the day.

Here were the biggest draws and drivers for big-time payouts over the course of Week 10:

  1. QB Justin Herbert (LAC)
  2. QB Aaron Rodgers (PIT)
  3. RB Christian McCaffrey (SF)
  4. WR Ladd McConkey (LAC)
  5. RB Jaylen Warren (PIT)
  6. WR DK Metcalf (PIT)
  7. TE Oronde Gadsden II (LAC)
  8. WR Amon-Ra St. Brown (DET)
  9. RB James Cook III (BUF)
  10. RB Jahmyr Gibbs (DET)

10 NFL Players Who Drove the Most Payout in Week 10 on Pick6

  1. WR Ladd McConkey (LAC)
  2. RB Jonathan Taylor (IND)
  3. RB Jahmyr Gibbs (DET)
  4. RB Christian McCaffrey (SF)
  5. QB Justin Herbert (LAC)
  6. QB Daniel Jones (IND)
  7. RB Bijan Robinson (ATL)
  8. RB Kyren Williams (LAR)
  9. QB Caleb Williams (CHI)
  10. QB Aaron Rodgers (PIT)
  1. Ladd McConkey MORE Receiving Yards
  2. Oronde Gadsden II MORE Receiving Yards
  3. Jaxon Smith-Njigba MORE Receiving Yards
  4. DK Metcalf MORE Receiving Yards
  5. Amon-Ra St. Brown MORE Receiving Yards
  6. Aaron Rodgers MORE Passing Yards
  7. Jonathan Taylor MORE Rushing + Receiving Touchdowns
  8. Christian McCaffrey MORE Rushing + Receiving Touchdowns
  9. Justin Herbert MORE Rushing Yards
  10. James Cook III MORE Rushing + Receiving Touchdowns

10 Week 10 NFL Pick6 Picks That Drove the Most Payout

  1. Christian McCaffrey MORE Receiving Yards
  2. Bijan Robinson MORE Rushing Yards
  3. Jaxon Smith-Njigba MORE Rushing + Receiving Touchdowns
  4. Jameson Williams MORE Receiving Yards
  5. Matthew Stafford MORE Passing Yards
  6. Drake London MORE Receiving Yards
  7. Ladd McConkey MORE Receiving Yards
  8. Kyren Williams MORE Rushing Yards
  9. T.J. Hockenson LESS Receptions
  10. Daniel Jones MORE Passing Yards

Sam Connon
Sam joined DraftKings in 2025 following five years with Sports Illustrated’s “On SI” network. He has covered the UCLA Bruins, New England Patriots, Tampa Bay Rays, MLB, MiLB and NBA, on top of earning awards from the Society of Professional Journalists and College Media Association during his time as a student at UCLA.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.