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Best College Football player prop bets for USC Trojans vs. Northwestern Wildcats on Friday 11/07/25

Best College Football player prop bets for USC Trojans vs. Northwestern Wildcats on Friday 11/07/25

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By: Dan Johnson

Friday in Los Angeles glows beneath the Coliseum torch as No. 19 USC hosts a stubborn Northwestern under FOX lights. It’s a rare reunion after decades apart, now carrying Big Ten weight and USC’s playoff urgency. The market pins −14.5 with a 51.5 lid, signaling controlled pace and ruthless efficiency over chaos. USC rides 505.9 yards and 39.8 points with 92.3% red-zone finish; Northwestern counters 16.8 allowed and 33:23 control. Short-week USC returns 4–0 at home while bye-fed Northwestern brings fresh legs; expect fireworks versus sandpaper and exploitable edges. Below are my top college football player props to consider for the Week 11 matchup between the USC Trojans and the Northwestern Wildcats.

Here’s how I’ll play it. I’ll be pumping out these predictions for individual games all season, with plenty of coverage here on DraftKings Network. Follow my handle @dansby_edits for more betting plays.

USC vs. Northwestern best prop bets

King Miller 110+ rushing yards (-105)

profiles as USC’s clock-and-crease hammer in this matchup. The Trojans average 203.6 rushing yards and play from script at home as a two-score favorite. Lincoln Riley leans ground when leverage tilts; short fields and a lead feed carries. Miller owns 509 yards on 65 totes at 7.8 YPC, explosive yet repeatable in USC’s split-flow run menu. He just posted 129 at Nebraska and 158 against Michigan, proof of runway when boxes lighten.

Northwestern’s shell caps explosives through the air and concedes efficient boxes by design. That philosophy pairs with USC’s down-to-down edge: 51.6% on third down sustains drives and preserves volume. In the strike zone, USC finishes 92.3% of red-zone trips, which forces the Wildcats to respect quarterback keepers. That respect widens the B-gap and gifts Miller daylight on duo and inside zone. He doesn’t need breakaways; he stacks fives and sevens until the total swells.

Tempo and game state cooperate. USC’s 4–0 home form and 39.8 points per game invite a fourth-quarter salt job. Northwestern’s offense prefers 33:23 possession, but USC’s front has 32 sacks and can flip fields quickly. If USC reaches seven meaningful possessions, Miller’s path to 110+ rides sustained snaps, not variance. Missed tackles grow late when cardio thins under Los Angeles lights.

I’m on King Miller 110+ rushing yards (−105) as a primary. The script, the percentages, and his 7.8 YPC argue for volume plus efficiency.

Caleb Komolafe 80+ rush yards (+104)

Northwestern’s identity is unapologetic math: 187.9 rushing yards per game and 33:23 possession that throttles tempo and steals series. Komolafe owns 608 yards at 4.9 YPC with seven touchdowns, a north–south style that punishes late fills and arm tackles. He just stacked 125 on 17 carries, which screams efficiency and fresh legs off the bye. USC’s front has talent and 32 sacks, but rush lanes widen when edges chase splash; on the ground they concede 143.1 per game. Nebraska carved 188. Notre Dame ripped 306. Those scars map directly onto Northwestern’s menu.

David Braun will lean duo and inside zone, then window-dress with orbit and sift to tug linebackers a half-gap. That sequencing manufactures second-and-five and keeps Preston Stone clean from obvious must-throw downs. Discipline completes the loop: Northwestern yields only 28.5 penalty yards per game, so drive scripts stay on schedule and first-read runs stay live. Every clean snap converts into Komolafe attempts, not hopeful shots into a secondary that thrives on tips. The Wildcats want body blows early and a tilt in pursuit angles late, when legs fade and angles blunt under L.A. lights. If Northwestern reaches four sustained possessions before halftime, Komolafe’s runway to 80+ becomes less sweat and more clock math.

Jayden Maiava to score a touchdown (-135)

Jayden Maiava owns a red-zone lever this matchup can’t ignore. He has five rushing touchdowns and a frame that finishes contact. USC converts 51.6% on third down and scores on 92.3% of red-zone trips. That efficiency multiplies goal-to-go snaps where quarterback keepers punish overflows. Northwestern plays excellent defense, allowing 16.8 points, but yields 42.4% on third down. Extra conversions equal extra tries from the three. King Miller’s 7.8 YPC forces softened edges and displaced overhangs. When linebackers fit Miller, Maiava pulls and walks the alley.

USC averages 203.6 rushing yards, so the script stays ground-forward as a two-score favorite. Home oxygen and tempo control amplify red-zone volume across four quarters. I’m on Maiava anytime TD (−135); Up ladder: 2+ TDs (+450) if you’re building a USC runaway that leans Miller volume and condensed-box theft near the goal line.

Dan Johnson has been an editor, writer, and analyst for DraftKings and DraftKings Network since 2024. He’s previously held editorial posts at The Paris Review, Macmillan Publishers, Bedford/St. Martin’s Press, ASSIGNMENT Magazine, and FantasySixPack. You can find his various editorial work & writing (sports-related and non-) at all of the above.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is thegreatdansby9) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.