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Top DraftKings Pick6 NFL Picks: Most Popular Plays from Week 5

Top DraftKings Pick6 NFL Picks: Most Popular Plays from Week 5

DraftKings Fantasy Advice Pick6 NFL

Published:

By: Sam Connon

With Sunday in the rear-view mirror, another DraftKings Pick6 contest has come and gone. Whether the NFL players themselves came in above or below their projected lines, there were winners on all sides.

Every week, we’ll be taking a look at which players and plays helped the most NFL Pick6 lineups. Stefon Diggs’ return to Buffalo to face the Bills in a Patriots uniform was a popular pick that paid off, while Josh Allen and Drake Maye came through, as well. Before the primetime window hit, Justin Jefferson and Jonathan Taylor were among the stars who delivered.

Here were the biggest draws and drivers for big-time payouts over the course of Week 5:

  1. QB Josh Allen (BUF)
  2. RB James Cook III (BUF)
  3. QB Drake Maye (NE)
  4. WR Stefon Diggs (NE)
  5. TE Dalton Kincaid (BUF)
  6. WR Justin Jefferson (MIN)
  7. WR Garrett Wilson (NYJ)
  8. WR Khalil Shakir (BUF)
  9. RB Quinshon Judkins (CLE)
  10. RB Jonathan Taylor (IND)

10 NFL Players Who Drove the Most Payout in Week 5 on Pick6

  1. QB Josh Allen (BUF)
  2. QB Drake Maye (NE)
  3. WR Stefon Diggs (BUF)
  4. WR Garrett Wilson (NYJ)
  5. WR Justin Jefferson (MIN)
  6. TE Dalton Kincaid (BUF)
  7. QB Jared Goff (DET)
  8. RB Jonathan Taylor (IND)
  9. QB Jaxson Dart (NYG)
  10. RB Quinshon Judkins (CLE)
  1. Stefon Diggs MORE Receiving Yards
  2. James Cook III MORE Rushing + Receiving Touchdowns
  3. Khalil Shakir MORE Receiving Yards
  4. Dalton Kincaid MORE Receiving Yards
  5. Garrett Wilson MORE Receiving Yards
  6. James Cook III MORE Rushing Yards
  7. Josh Allen MORE Passing Yards
  8. Jaylen Waddle LESS Receptions
  9. Drake Maye MORE Passing Yards
  10. Jonathan Taylor MORE Rushing + Receiving Touchdowns

10 Week 5 NFL Pick6 Picks That Drove the Most Payout

  1. Garrett Wilson MORE Receptions
  2. A.J. Brown MORE Receptions
  3. Garrett Wilson MORE Receiving Yards
  4. Tua Tagovailoa MORE Rushing Yards
  5. Stefon Diggs MORE Receiving Yards
  6. Josh Allen MORE Passing Yards
  7. Drake Maye MORE Passing Yards
  8. Zach Charbonnet LESS Rushing Yards
  9. Jake Ferguson MORE Receptions
  10. Woody Marks LESS Rushing Yards

Sam Connon
Sam joined DraftKings in 2025 following five years with Sports Illustrated’s “On SI” network. He has covered the UCLA Bruins, New England Patriots, Tampa Bay Rays, MLB, MiLB and NBA, on top of earning awards from the Society of Professional Journalists and College Media Association during his time as a student at UCLA.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.