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Opening Odds for Chicago Cubs vs. San Diego Padres Game 3 of 2025 NL Wild Card

Opening Odds for Chicago Cubs vs. San Diego Padres Game 3 of 2025 NL Wild Card

Sports Betting Picks MLB DraftKings Sportsbook Insights

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By: Charlie Cummings

In Game 1 of this Wild Card Series, the Cubs’ bullpen was nails to deliver a home win and put the Padres on the ropes. San Diego’s relievers returned the favor on Wednesday by pitching 5.1 scoreless innings — allowing only one baserunner — to deliver a crucial win. Mason Miller was the chief architect, striking out all five batters he faced in surreal fashion.

Now it’s time for a win-or-go-home Game 3 on Thursday, where the winner advances to take on the Milwaukee Brewers in the NLDS.

The odds are virtually even for Game 3 on DraftKings Sportsbook, with the Cubs at -116 and the Padres at -105 on the moneyline. The Cubs turn to Jameson Taillon as the starter in this winner-take-all contest, while the Padres will send Yu Darvish to the mound. The total for this game is set at 7.5 runs.

Charlie Cummings

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.