The NFL season is already onto Week 4 and there are far more ways to get involved in the action than just via traditional betting. One of the more unique features on DraftKings this season is Pick6 Fantasy Football!
Here are my top Pick6 plays for Thursday Night Football.
Kyler Murray More Than 28.5 Rushing Yards

Kyler Murray is off to a strong start this season. He ranks 11th among 33 qualified quarterbacks in adjusted EPA/play and has the Cardinals off to a 2-1 start. They came up just short in Week 3 against the 49ers, nearly starting the season a perfect 3-0. Their two wins came against the Panthers and Saints, and they got to face a Brock Purdy-less 49ers team, so this will be their toughest matchup of the season against Seattle. It will be made tougher by the fact that the Cardinals will be without their star running back James Conner, who went down with an injury against San Francisco. Without Conner, the Cardinals will likely lean more heavily on Kyler Murray’s legs in this game. They will likely call less running plays, giving Murray more chances to scramble, but also give Kyler Murray more designed runs than they normally would. Murray has already cleared this number in all three games this season, rushing for at least 32 yards in each game. This should be a game where Murray gets more rushing attempts, so he should clear this number for the fourth straight game.
Trey Benson More Than 0.5 Rushing + Receiving TDs

Trey Benson is stepping in as the primary running back for Arizona, with James Conner sidelined with his injury. This is Benson’s second season with the Cardinals after being drafted in the third round in 2023. James Conner has been an incredibly consistent back for Arizona, staying on the field and producing at a high level. That presented little opportunity for Benson in his rookie season. However, this is now his big change to prove himself as a reliable NFL running back. Benson was a star at Florida State, scoring 15 total touchdowns in his final season with the Seminoles. He should be able to find the end zone in this game as well, in his first game as an NFL starter. The Seahawks’ have a dangerous secondary, and the Cardinals will try to keep the ball on the ground as much as possible. The threat of Kyler Murray’s legs is always looming when the Cardinals get close to the end zone, so that should help to get Benson a good pathway for a touchdown.
Tory Horton More Than 21.5 Receiving Yards

Tory Horton had a monster game in Week 3 against the Saints. The rookie had a receiving touchdown and a 95-yard punt return touchdown in his third NFL game. After not having a catch in Week 1 against the 49ers, Horton has established himself as the clear WR3 behind superstar Jaxon Smith-Njigba and the veteran, Cooper Kupp. Horton has electric speed, as evidenced by his punt return touchdown, but also has great hands to be a possession receiver for Sam Darnold. Horton has 32 receiving yards in each of his past two games, comfortably clearing this 21.5-yards mark. He should keep that going against Arizona. The Cardinals’ defense ranks 28th in the NFL in defensive dropback success rate, despite playing Bryce Young, Mac Jones and Spencer Rattler the first three weeks. Sam Darnold and the Seahawks’ passing attack will be by far the biggest test they have had to face, and they might really struggle to slow them down. Smith-Njigba and Kupp demand so much attention, that it should be another game where Horton can be the one getting open and making plays.
What is DraftKings Pick6?
Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of 2+ players and select whether you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.
How to Play
Create a Pick Set
Create a Pick Set by choosing 2+ players from the same sport and Pick Group (a set of picks available from a group of set competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you can not pick the same player twice, and you must pick players from at least two different teams.
Enter an Amount
Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.
Sweat Your Picks
When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.
Compete for Prizes
Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.
Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!
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