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DraftKings TNF Pick6 Fantasy Football Picks: Top Plays for Thursday Night Football Week 1

DraftKings TNF Pick6 Fantasy Football Picks: Top Plays for Thursday Night Football Week 1

Published:

By: Blake Krass

The 2025-26 NFL season begins tonight. There are far more ways to get involved in the action than just via traditional betting. One of the more unique features on DraftKings this season is Pick6 Fantasy Football!

Here are my top Pick6 plays for Thursday Night Football.

Dak Prescott More Than 0.5 Passing Yards (Promo Pick)

DraftKings Pick6 is offering an incredible promotion for the first night of the NFL season. Players can get Dak Prescott to throw for more than 0.5 passing yards at 1x. As long as Prescott completes a pass, this pick will increase the winnings if the rest of your plays hit. It is a chance to boost the winnings on your first Pick6 entry of the NFL season that can’t be passed up.

Jalen Hurts More Than 0.5 Rushing + Receiving TDs

Since 2021, Jalen Hurts leads the NFL in rushing touchdowns, with one more than Derrick Henry over that span. Despite some NFL teams’ best efforts, the “tush push” was not banned this offseason. That means Hurts should continue his absurd rushing touchdown production. The threat of Saquon Barkley, as well as the Eagles’ receivers, often leaves Jalen Hurts a clear path to scramble for touchdowns or take it himself on a designed run. Then, of course, he racks up the rushing touchdowns on the “tush push.” If the Eagles are within two yards of the end zone, they’re going to let Hurts sneak it and he almost always finds the end zone. Hurts had two rushing touchdowns in the one game he played against Dallas last season, and he should get at least one more in this game.

CeeDee Lamb More Than 73.5 Receiving Yards

CeeDee Lamb is unquestionably one of the five best receivers in the NFL. Since coming into the league in 2020, he ranks fourth in the NFL in receiving yards, behind only Justin Jefferson, Tyreek Hill and Davante Adams. Over the last two seasons, he is the NFL receiving yards leader with 2,943 yards. That is despite one of those seasons being largely without starting quarterback Dak Prescott. Even with Cooper Rush at the helm, Lamb was still able to produce last season. However, with a healthy Prescott in 2023-24, Lamb was on another level, averaging over 100 receiving yards per game. The Eagles have a fantastic defense and will make life tough for Lamb, but the addition of George Pickens should take at least a bit of the defensive attention off Lamb this season. The last time Lamb played in Philadelphia, he had 11 catches for 191 yards. He might not hit those numbers again, but he should get over this mark to open the season.

Saquon Barkley More Than 19.5 Rush Attempts

Saquon Barkley was the NFL Offensive Player of the Year last season. It was a special year, resulting in a Super Bowl victory in Barkley’s first season with the Eagles. After resting the entire preseason, Barkley should be fresh and ready for this game. Including the postseason, Barkley averaged 21.8 rushing attempts per game last season. For being such an elite athlete, Barkley is rarely used in the passing game. The Eagles want to give him the ball in the backfield and let him work his magic. His final game of the 2024-25 regular season was at home against the Cowboys, and he carried the ball 31 times in that game. He toted the ball 24 times in the season opener against the Packers as well. The Eagles’ offense should see no change from last season. If they’re winning, they’ll give Barkley the ball to ice the game, and if it’s tight, they’ll put the ball in Barkley’s hands to win them the game. Either way, he should get over 19.5 rush attempts against the Cowboys.


What is DraftKings Pick6?

Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of 2+ players and select whether you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.

How to Play

Create a Pick Set

Create a Pick Set by choosing 2+ players from the same sport and Pick Group (a set of picks available from a group of set competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you can not pick the same player twice, and you must pick players from at least two different teams.

Enter an Amount

Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.

Sweat Your Picks

When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.

Compete for Prizes

Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.


Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!

Blake Krass has contributed to DraftKings since 2024, and is a content creator with a specialty in sports betting. Blake primarily focuses on college football and NFL coverage but will also be covering college basketball, the NBA, MLB and more. Prior to arriving at DK, Blake was a sports betting writer for The Action Network.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and customer (my username is blakekrass) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.