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Colorado Rockies vs. St. Louis Cardinals prediction, pick for Monday 7/21/25

Colorado Rockies vs. St. Louis Cardinals prediction, pick for Monday 7/21/25

Published:

By: Dan Johnson

How about some dingers into the thin-air void at Coors tonight? Maybe a Brendan Donovan game? What else do you want me to say. This isn’t exactly the most exciting tilt on the slate. Below, I’ve got my preview, prediction, and best bet for this Monday night baseball game between the Rays and the White Sox.

Here’s how I’ll play it. I’ll be pumping out these predictions for individual games all season, with plenty of coverage here on DraftKings Network. Follow my handle @dansby_edits for more betting plays.

Rockies vs. Cardinals prediction, preview

Coors Field inflates run scoring, but both staffs offer value on the under. Michael McGreevy pitches for St. Louis. He has a 4.22 ERA and 1.03 WHIP in 21.1 innings. He showcases strong strike‑to‑walk ratio and grounder rate. He thrives with command and induces weak contact. Rockies batters struggle against his mix of sinker and sweeper. McGreevy held MLB hitters under average before this road matchup.

Cardinals hitters hit .235 in July and generate weak slugging. They rank just 20th in wRC+. That plays into a lower‑scoring game. Austin Gomber starts for Colorado. He owns a 5.65 ERA and just 4.4 K/9 innings. Opponents hit .320 off him overall. Coors Field boosts his struggles; he hasn’t delivered a quality start. His career ERA at home tops 7.00. That leaves early innings unpredictable.

But bullpen depth dynamic favors under total. Cardinals relief staff holds ERA under league median. Rockies pen ranks near bottom at Coors in fatigue and mistakes. Expect minimal late scoring. Historical trends reinforce the under. Seven of Rockies’ last eight NL games went below total. The Rockies embody run-suppression patterns.

Cardinals vs. Rockies pick, best bet

And the true edge lies in run suppression. Both squads scored seven runs across Cardinals’ last road series. Rockies rank dead last in wRC+. Cardinals haven’t offered reliable offense recently.

They scored just seven runs in three games on their Arizona trip. That means low output is expected tonight. Brendan Donovan needs bounce back after 0‑for‑4 last game. He hits .291 with 22 doubles and eight home runs. He reaches base in 71.7% of games and racks multiple hits in 25% of matchups. But he’s 0‑for‑4 career versus Gomber. That compounds wide plate discipline with no early spark.

Alec Burleson carries a four‑game hit streak, batting .313 in last five. He provides some pop but not team-saving power. On Colorado side, Hunter Goodman leads with .279 average and 18 homers. He supplies power but Rockies restrict overall scoring. Both offenses feature individual firepower but lack consistency. Staffs and bullpens make under the smart play.

Forecast the whole shebang for modest wind, strong pitchers, and limited offense that’ll fit tonight’s script. Game conditions support under output. Bookmakers set total high at 11.5 but line movement signals lower.

Best bet: Rockies vs. Cardinals u11.5 total runs (-105)

Tail it with me in the DKN Betting Group here!

Dan Johnson has been an editor, writer, and analyst for DraftKings and DraftKings Network since 2024. He’s previously held editorial posts at The Paris Review, Macmillan Publishers, Bedford/St. Martin’s Press, ASSIGNMENT Magazine, and FantasySixPack. You can find his various editorial work & writing (sports-related and non-) at all of the above.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is thegreatdansby9) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.