The 2025 MLB season is heating up and there are far more ways to get involved in the action than just via traditional betting. One of the more unique features on DraftKings this year is Pick6 Fantasy Baseball!
Here are my top Pick6 plays for today’s MLB slate.
Rafael Devers More Than 0.5 At Bats (Promo Pick)
Rafael Devers is facing off against his former team for the first time since the blockbuster trade that sent him to San Francisco. In honor of this showdown, DraftKings Pick6 is giving all customers a promo pick for the ages. All you need is for Devers to take one at-bat to cash this selection in your Pick6.
Ketel Marte More Than 2.5 Total Bases
Ketel Marte is having another monster season for Arizona. Last year, Shohei Ohtani and Francisco Lindor had an epic battle for the NL MVP, but it was Marte who came in third in that race behind those two greats. Marte finished the season with a 155 OPS+. This season, he has a 161 OPS+, putting him on pace to top last year’s numbers. Marte missed a chunk of time early, which could prevent him from being in the MVP race again. However, Marte is undoubtedly one of the best hitters in baseball. Tonight, he gets to face Austin Gomber in Colorado. Gomber is making just his second start of the season, but he has had an ERA of 4.53 or higher in all four of his seasons in Colorado. The Rockies also have a bottom-five bullpen in the MLB, measured by bullpen ERA. Marte should get multiple hits in this game and clear 2.5 total bases.
Juan Soto More Than 0.5 RBIs
Juan Soto is quietly starting to bolster his season numbers. Soto has been criticized at times for his slow start in the first year of his historic Mets contract. Over the past two weeks, Soto is batting .349 with a 1.086 OPS. He’ll look to continue that form this weekend against the Phillies. The Mets are slumping hard and need to have a good series in Philadelphia, as the teams are currently tied atop the NL East. Soto should be able to provide a spark against the tough Zack Wheeler. Wheeler is a great pitcher, but Soto has held his own against him in the past. He has a .418 on-base percentage in his career against Wheeler and has three home runs off the right-hander. The Phillies also rank 23rd in baseball in bullpen ERA, so Soto will be able to jump on them once Wheeler exits the game. Soto has six RBIs in his past nine games, and should be able to keep it rolling tonight.
Fernando Tatis Jr. More Than 7.5 Batter Fantasy Points
Fernando Tatis Jr. is having another great season in San Diego. Tatis has a 125 OPS+ this season and has consistently delivered strong production for the Padres. He is hitting home runs, getting on base, stealing bases and, most importantly, getting runs on the board. Tatis ranks fifth in the MLB in runs scored this season and is tied for eighth in WAR. He has been red hot over the past week, sporting a .950 OPS across his past seven games. After a tough series against the Dodgers, Tatis will be happy to see Michael Lorenzen on the bump for Kansas City. Lorenzen has a 4.91 ERA this season and it has been even worse recently, with a 7.40 ERA over his past five starts. Tatis also has a 125 tOPS+ at home this season. He’s in a fantastic spot, if he’s able to play after being drilled in the hand by a pitch late Thursday evening.
Andre Pallante More Than 3.5 Strikeouts Thrown
Andre Pallante has had an up-and-down 2025 season. He has made some great starts, but also some starts that he will hope to forget. Tonight, he takes on the Reds in an NL Central battle in St. Louis. Pallante is averaging 6.4 strikeouts per nine innings this season and has gone over 3.5 strikeouts in four of his past seven starts. The Reds are a team that strikes out a lot, ranking sixth in the MLB in team strikeouts this season. Some of the big bats in the Reds’ lineup have struggled against Pallante in the past, as well. Spencer Steer, Elly De La Cruz, Matt McLain, Will Benson, Austin Hays and TJ Friedl are a combined 7-for-52 (.134) against Pallante in their careers. Earlier this season, in Cincinnati, Pallante faced the Reds and turned in a quality start while striking out four batters. He should be able to repeat that performance, or better, at home to cash this pick.
Jeremy Pena More Than 0.5 Runs
Jeremy Pena is having a great season in Houston. It has been by far his best-career season at the plate, sporting a 139 OPS+ in 2025. He is batting .322, the sixth-best mark among qualified hitters in all of Major League Baseball. Once Pena gets on base, he can use his speed to turn that into runs scored, with 44 already this season. The left-handed Yusei Kikuchi is on the mound for the Angels tonight. Pena has a 127 tOPS+ against left-handed starting pitchers this season. Kikuchi has allowed three runs in two of his past three starts. Pena should be able to get on base against Kikuchi and score a run. Even if he can’t do it against Kikuchi, the Angels have the fourth-worst bullpen in baseball, measured by bullpen ERA.
What is DraftKings Pick6?
Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of two or more players and select whether you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.
How to Play DraftKings Pick6
Create a Pick Set
Create a Pick Set by choosing two or more players from the same sport and Pick Group (a set of picks available from a group of set competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you cannot pick the same player twice and you must pick players from at least two different teams.
Enter an Amount
Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.
Sweat Your Picks
When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.
Compete for Prizes
Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.
Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!
