Panthers vs. Saints NFL Player Prop Bets for Week 10

Sunday afternoon’s loaded NFL Week 10 slate features an NFC South showdown between the Carolina Panthers and the New Orleans Saints at Caesars Superdome, with kickoff set for 1 p.m. ET.

The Panthers (3–5, 1st NFC South) have dropped three straight, capped by a 26–21 home loss to the Denver Broncos. The Saints (3–5, 1st NFC South) have won two of their last three, most recently notching a 23–22 overtime win at home against the Cleveland Browns. 

New Orleans is a 2.5-point home favorite with -130 moneyline odds on DraftKings Sportsbook. Carolina is a +110 underdog, with the game total set at O/U 48.5 points. 

Let’s dive into the top player prop bets for Sunday’s clash between the Panthers and the Saints. 

Panthers vs. Saints NFL Player Prop Bets on DraftKings Sportsbook

Chuba Hubbard | 80+ Rush Yards (-112)

Chuba Hubbard has put his disappointing 2025 campaign firmly in the rearview. The 27-year-old running back has already matched his rushing workload from last season after just eight games, handling 134 carries for 619 yards (4.6 YPC) and five rushing touchdowns. He’s also added 26 catches for 167 yards and two scores. 

Hubbard has rushed for 80+ yards in four of his last six games, finishing with 79 in Carolina’s Week 9 matchup against the Broncos. He now faces a similarly dysfunctional run defense from New Orleans, which has hemorrhaged 11 rushing TDs and a whopping 133.9 rushing yards per game — the fourth-most in the NFL.

Chris Olave | 6+ Receptions (-144)

Tyler Shough isn’t even trying to hide who his favorite receiver is. The second-year quarterback has formed a lethal connection with Chris Olave, who ranks seventh in the NFL with 56 receptions (on 83 targets), taking them for 734 yards and two touchdowns. 

Olave, 26, has seen double-digit targets in six of his eight games this season — piling up 6+ catches in each of them. He’s met that mark in back-to-back contests heading into Sunday afternoon. Although the Panthers have been decent against the pass this season, Olave’s ridiculous target volume should keep him busy in Week 10.