Looking for #16 SMU Mustangs vs. #23 Louisville Cardinals betting trends and odds? Below you’ll find the latest DraftKings Sportsbook Point Spread, Total and Moneyline betting percentages, plus where the public and sharp money are landing before kickoff on Saturday.
SMU vs. Louisville Best Picks Today
- Louisville -1.5 Point Spread (-110): Louisville is attracting 72% of handle on just 50% of bets, a 22-point gap that signals sharp money backing the home favorite to win by more than a possession.
- Kendrick Raphael (SMU) 3+ Touchdowns (+1600): The SMU playmaker carries the shortest 3+ TD odds on the Mustangs’ side in a game with a 58.5-point total, giving him the scoring environment for a multi-touchdown performance.
Game Info
| Kickoff | Saturday, September 19 at 3:30 PM ET |
| Venue | L&N Federal Credit Union Stadium, Louisville, KY |
| TV | ESPN2 |
SMU vs. Louisville Odds
| Market | Cardinals (Home) | Mustangs (Away) |
|---|---|---|
| Point Spread | -1.5 (-110) | +1.5 (-110) |
| Total | Over 58.5 (-112) | Under 58.5 (-108) |
| Moneyline | -118 | -102 |
DraftKings Betting Trends
| Market | Side | Bets % | Handle % |
|---|---|---|---|
| Point Spread | Louisville -1.5 | 50% | 72% |
| Point Spread | SMU +1.5 | 50% | 28% |
| Total | Over 58.5 | 91% | 98% |
| Total | Under 58.5 | 9% | 2% |
| Moneyline | Louisville | 52% | 78% |
| Moneyline | SMU | 48% | 22% |
Louisville’s Point Spread draws a 22-point gap between handle (72%) and bets (50%), the clearest sharp indicator on the board for this game. While tickets are split evenly, the money heavily favors Louisville to cover, suggesting professional bettors see the Cardinals winning by at least a field goal at home.
Key Matchup Numbers
- Massive sharp lean on Louisville: The 22-point handle-vs-bet gap on Louisville -1.5 is one of the largest spread discrepancies of the week, pointing to professional money backing the home favorite to cover a razor-thin number.
- Over consensus backed by both public and sharps: Handle at 98% on Over 58.5 with 91% of bets confirms this is one of the rare markets where recreational and sharp bettors are fully aligned on a high-scoring outcome.
- Near pick’em Moneyline hides directional money: Louisville is just -118 on the Moneyline, but 78% of handle is flowing its direction, a 26-point gap over its 52% bet share that reinforces the sharp lean.
DraftKings Player Props
- Isaac Brown (LOU) 3+ Touchdowns (+1800): the Louisville skill player carries the shortest 3+ TD odds among Cardinals players in a game projected for nearly 60 combined points
- Kendrick Raphael (SMU) 3+ Touchdowns (+1600): the shortest 3+ TD price on the SMU roster, reflecting his expected role as the Mustangs’ primary scoring threat
- Lincoln Kienholz (LOU) 3+ Touchdowns (+2500): the Louisville quarterback offers multi-TD upside in a high-scoring home affair with a 58.5 total
- Keyjuan Brown (LOU) 3+ Touchdowns (+2000): another Louisville scoring option with a reasonable 3+ TD price given the game environment
Featured Parlays
FAQs
What are the SMU vs. Louisville odds this week?
Louisville, ranked No. 23, is a 1.5-point favorite at DraftKings Sportsbook, with the Point Spread set at Louisville -1.5 (-110). The Total is set at 58.5, and Louisville is -118 on the Moneyline.
What are CFB betting trends?
Betting trends show how the public is wagering on a game by breaking down the percentage of total bets (tickets) and total money (handle) on each side of a market. They help identify which side recreational bettors favor versus where larger, potentially sharper money is landing.
What is the difference between bets and handle?
Bets refer to the number of individual tickets placed, while handle represents the total dollar amount wagered. A side with low bet percentage but high handle percentage suggests fewer bettors placing larger wagers, often interpreted as sharp or professional action.
How do betting trends identify sharp money?
Sharp money refers to wagers placed by professional or highly informed bettors. It is typically identified through handle-vs-bet discrepancies: when a side draws a disproportionate share of money relative to its ticket count, sharps are likely involved.