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Wrexham vs. Southampton prediction, pick for Saturday 9/19/26

Wrexham vs. Southampton prediction, pick for Saturday 9/19/26

Published:

By: Blake Krass

There is a great Saturday fixture in the Championship. Southampton is headed to Wales to take on Wrexham. These are two clubs that entered the season with Premier League aspirations, but have not quite hit the ground running.

Southampton is a +135 favorite on DraftKings Sportsbook for this one, with a draw available at +255. Wrexham are +200 to pull off the home upset and take all three points. This is my prediction and pick for the Championship tie between Southampton and Wrexham.


Wrexham vs. Southampton Prediction

Southampton Preview

This is a massive season for Southampton. They seemed on the brink of promotion to the Premier League last season before controversy struck. The well-documented Southampton Spygate saga saw them kicked out of the Championship final. The Saints are now under immense pressure from all sides to get promoted this season. Their fanbase is desperate to prove everyone wrong, and opposing fanbases are ripping into Southampton everywhere they go. It will be no different on this trip to Wrexham. Southampton still has one of the most talented squads in the Championship and could get back to the Premier League next season.

Wrexham Preview

Wrexham has been one of the best stories in sports over the past few years. It has been a meteoric rise up the English football pyramid to the second division. After a series of promotions, Wrexham finally hit a wall last season in the Championship. However, they still had a very respectable seventh-place finish in their first season in the Championship. This season has not quite gone according to plan for The Reds. They currently sit in 19th place and have only won one of their first seven matches. Wrexham need to get things back on track if they want to fight for promotion again this season.

Wrexham vs. Southampton Pick

My best bet is on the Southampton Moneyline. After a bit of a mixed start to the season, Southampton have been scoring in bunches as of late. They have won each of their past two matches, with a combined score of 7-2. Southampton have not conceded more than one goal in any of their past five matches. They rank second in the Championship in goals scored so far this season and should put up a couple of goals against Wrexham. The Reds are coming off a tough 6-0 loss to West Ham. Something is just not right with Wrexham and Southampton should take advantage of this tough mo

Best Bet: Southampton ML (+135)


Blake Krass has contributed to DraftKings since 2024, and is a content creator with a specialty in sports betting. Blake primarily focuses on college football and NFL coverage but will also be covering college basketball, the NBA, MLB and more. Prior to arriving at DK, Blake was a sports betting writer for The Action Network.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.