The 49ers are facing the Rams on Thursday night in Australia for the first edition of Thursday Night Football for the 2026-27 season. On DraftKings Sportsbook, Los Angeles is favored by 3.5 points and this game carries a total of 48.5 points.
Below, I break down my favorite Christian McCaffrey prop bet for Thursday night’s matchup, focusing on his receiving yards line against the Rams.
Christian McCaffrey Receiving Yards Prop Bet vs. Rams
Christian McCaffrey O 41.5 Receiving Yards (-109)
McCaffrey was the best receiving back in the NFL last season, leading all backs in receiving yards between the regular season and the playoffs (1,029). McCaffrey topped 41.5 receiving yards in 13-of-19 games and he saw 135 targets, which was the most among running backs by a mile. Ranking second was Bijan Robinson at 99.
McCaffrey saw a target on 24% of his routes and he ranked third at his position in YPPR (1.81). As division rivals, the 49ers faced the Rams twice last season and McCaffrey was tremendous as a pass catcher in these matchups, providing 82 and 66 receiving yards.
The Rams were very susceptible to receiving backs last season, allowing the fifth most receiving yards to the position (650), and McCaffrey should expose them for another big receiving day Thursday night.
The 49ers are a 3.5-point underdog on DraftKings Sportsbook – which will likely lead to a pass heavy game plan – and McCaffrey averaged 59.4 receiving yards per game when competing as an underdog last season (eight games).
