DKNetwork Logo DKNetwork Logo
Los Angeles Chargers vs. Los Angeles Rams prediction, pick for NFL Preseason on 8/27/26

Los Angeles Chargers vs. Los Angeles Rams prediction, pick for NFL Preseason on 8/27/26

Published:

By: Dan Johnson

The Rams have spent August flattening the usual distinction between roster locks and camp labor. Their 20-12 win at Kansas City preceded a 34-0 evisceration of New Orleans. They own the preseason’s highest point differential at +42, despite protecting at least 37 players in both games. Five more joined that class Saturday. The Chargers opened with a 27-7 mauling at Houston, then unraveled 41-17 against San Francisco. Jim Harbaugh called that performance sloppy across all three phases. His response supplies tonight’s defining deployment wrinkle. Justin Herbert and nearly every available starter will play six-to-nine snaps. Khalil Mack and Derwin James Jr. will sit. Sean McVay will again conduct an extended referendum on his roster’s bottom third. These neighbors share SoFi Stadium and meet again in Week 8. Expect vanilla playcalling, furious audition football, and sharply unequal personnel early. Below is my preview, prediction, and pick for today’s NFL preseason game between the Los Angeles Chargers and the Los Angeles Rams.

Here’s how I’ll play it. I’ll be pumping out these predictions for individual games all season, with plenty of coverage here on DraftKings Network. Follow my handle @dansby_edits for more betting plays.

Chargers vs. Rams prediction, preview

The Rams’ quarterback question has become deliciously complicated. Ty Simpson has completed 29-of-37 passes for 263 yards, two touchdowns, zero interceptions, and a 115.0 rating. His 78.4% completion rate and 7.1 YPA have accompanied zero sacks. Simpson shredded Kansas City for 190 yards, 7.6 YPA, and a 125.0 rating. Stetson Bennett followed with 181 yards against New Orleans, directing four scoring drives and rushing for two touchdowns. His overall 5.9 YPA and 78.5 rating still trail Simpson considerably. McVay confirmed three quarterbacks will make the initial roster, although Stafford’s Australia backup remains undecided. Simpson definitely plays; Bennett may not, and undrafted Matthew Caldwell could receive his first exhibition series. Caldwell introduces late volatility. Everything before him looks beautifully stable. The Rams have attempted 74 passes without allowing a sack or committing a turnover. Their reserve offense has played August with almost indecent composure.

Herbert’s cameo gives the Chargers an early hammer, especially against defenders McVay considers expendable enough to expose. It also doubles as an emergency installation period for Mike McDaniel’s reconstructed line. Tyler Biadasz’s torn ACL elevated second-round rookie Jake Slaughter into the starting center job. Rashawn Slater returns beside him after missing last season, while Kayode Awosika and Trey Pipkins III continue splitting left-guard work. Once Herbert leaves, the game becomes a wonderfully consequential quarterback duel. Trey Lance has completed 22-of-36 passes for 223 yards and an interception, adding 69 rushing yards. DJ Uiagalelei owns 200 yards, two touchdowns, 8.3 YPA, and a 109.7 rating across 24 attempts. Lance offers escape velocity; Uiagalelei has delivered the superior passing inventory. Harbaugh still calls their QB2 competition tight. Mike McDaniel’s reserves produced 379 yards and 23 first downs in Houston, then managed four first downs through three quarters against San Francisco. Tonight decides whether the opener or the collapse described them better.

Los Angeles’ deeper roster battles favor entertainment and aggression. Jarquez Hunter has rushed 21 times for 103 yards, strengthening his claim to the final running-back place. CJ Daniels’ eight-catch, 68-yard afternoon intensified a crowded WR6 argument involving Brennan Presley, Tyler Scott, and Xavier Smith. Edge rusher Wesley Bailey produced 10 pressures against New Orleans. Alex Cook returned an interception 100 yards, while Al’Zillion Hamilton converted extra practice work into another pick. The Rams have allowed 12 points, collected three takeaways, and surrendered only one offensive touchdown. New Orleans gained 293 yards and reached scoring territory repeatedly; turnovers converted every threat into ash. The Chargers’ opposing identity remains unresolved. Their defense forced seven Houston possessions to end within four plays, then conceded 41 points one week later. Jacob Cowing’s 83-yard punt return inflated that total, although San Francisco still outgained Los Angeles 321-229 through three quarters. Young edge rushers Nadame Tucker and Kyle Kennard now face their final examination without Mack absorbing attention.

Rams vs. Chargers pick, best bet

The scoring case rests on cleaner foundations than the side. The Rams have accumulated 54 points, 649 passing yards, and 244 rushing yards across two victories. Their offense has produced 4.8 yards per carry while avoiding every sack, interception, and lost fumble. Herbert should manufacture an early scoring opportunity against the Rams’ most disposable defensive combination. Lance’s 6.2 YPA looks ordinary, but his 9.9 yards per rush can rupture man coverage after scripted football disappears. Uiagalelei has already authored two touchdown passes and a two-point conversion. Amar Johnson scored twice in Houston, KeAndre Lambert-Smith produced 58 receiving yards, and Devonte Ross finished a fourth-quarter touchdown drive. Both coaching staffs also possess reasons to attack fourth downs. Sunday’s cutdown deadline rewards information, not conservative field-position management. SoFi removes weather entirely. The approaching regular-season rematch suppresses schematic imagination, yet these quarterbacks have sustained drives without needing exotic assistance.

The Chargers’ six-to-nine starting snaps cannot justify laying 3.5 points against an opponent this clean and deep. They can certainly help clear 38.5. Simpson owns the game’s best down-to-down passing profile, while Uiagalelei owns its most productive challenger. Bennett’s potential absence would remove a rushing red-zone weapon, though Caldwell appears unlikely before the closing quarter. Los Angeles has scored 27 points per game; the Chargers have averaged 22. A 38.5 total requires roughly 19 points from each side. Herbert’s opening drive, four capable reserve quarterbacks, and two aggressive roster evaluations provide several routes beyond that modest demand. The Rams defense deserves respect, although its 6.0-point average contains a 100-yard pick-six and repeated opponent self-destruction. Turnovers could also create short fields instead of suppressing scoring. I lean toward the Rams with the points. My stronger position backs both quarterback rooms to turn their respective audition stakes into offense.

Best bet: Over 38.5 (-105), playable through 39.5.

Projected score: Rams 23, Chargers 21.

Best Bet: Chargers vs. Rams o38.5 total points (-105)

Dan Johnson has been an editor, writer, and analyst for DraftKings and DraftKings Network since 2024. He’s previously held editorial posts at The Paris Review, Macmillan Publishers, Bedford/St. Martin’s Press, ASSIGNMENT Magazine, and FantasySixPack. You can find his various editorial work & writing (sports-related and non-) at all of the above.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is thegreatdansby9) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.