The MLB season is humming along. There are far more ways to get involved in the action than just via traditional betting. One of the more unique features on DraftKings this year is Pick6 Fantasy Baseball!
Here are my top Pick6 plays for today’s MLB slate.
DraftKings MLB Pick6 Plays
Ronald Acuna Jr. More Than 1.5 Hits + Runs + RBIs

It has been an up-and-down season on the mound for Anthony Kay in 2026. Kay has a 4.01 ERA and 1.34 WHIP this season. He has actually been excellent in lefty-on-lefty matchups, but has really struggled against right-handers. Righties are batting .280 with an .842 OPS against Kay this season. That is good news for Ronald Acuna Jr., one of the only pure right-handed batters in the Braves’ lineup. Acuna has not had his best season by any means. However, he is starting to find some consistency at the plate. In 17 games played this month, Acuna has at least one hit in 13 of them. Acuna also has five RBIs in his past five games. In this favorable matchup against Kay, Acuna should keep that consistency going and get over this number.
CJ Abrams More Than 1.5 Hits + Runs + RBIs

Jacob deGrom is taking the bump for the Rangers tonight against the Nationals. deGrom has had a decent season, but is not the dominant ace he once was. He has given up at least six hits in four of his past five starts. If any member of the Nationals is going to get the better of deGrom, it will be CJ Abrams. Abrams is batting .292 with a .950 OPS against right-handed pitching this season. Abrams has also been much better on the road this season, with a .960 OPS away from Washington. He is having a truly excellent season for the Nationals. Abrams ranks 22nd in the MLB in hits, 18th in runs scored and third in RBIs. The Rangers also have some major question marks in the bullpen, with the seventh-worst bullpen ERA in baseball this season. Abrams should be able to get over this number in Texas tonight.
Colton Cowser Less Than 0.5 Hits + Runs + RBIs

Gerrit Cole is taking the mound for the Yankees tonight. Cole has looked much more like himself as of late. An injury kept him out for a big chunk of the start of the season. After returning, he was not up to his usual standard. However, Cole now has a 1.46 ERA over his past four starts and has started to look dominant. He has been excellent against left-handed hitters all season. Lefties are batting just .205 against Cole in 2026. That is bad news for Colton Cowser, who is already having a rough season at the plate. Cowser is batting .212 with a .664 OPS this season. Cowser is also 0/7 in his career against Cole. Gerrit Cole should completely shut Cowser down, and keep him under this number for the fourth consecutive game.
What is DraftKings Pick6?
Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of 2+ players and select whether you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.
How to Play
Create a Pick Set
Create a Pick Set by choosing 2+ players from the same sport and Pick Group (a set of picks available from a group of competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you can not pick the same player twice, and you must pick players from at least two different teams.
Enter an Amount
Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.
Sweat Your Picks
When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.
Compete for Prizes
Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.
Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!
Gambling Problem? Call 1-800-GAMBLER. Must be at least 18 years or older. Higher age limits may apply in some states. Eligibility restrictions apply. Valid only in states where DraftKings Pick6 operates. Void where prohibited. For entertainment purposes only. Winning a contest on DraftKings depends on knowledge and exercise of skill. See terms at pick6.draftkings.com.