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DraftKings MLB Pick6 Fantasy Baseball Picks: Top Plays for Thursday 8/6/26

DraftKings MLB Pick6 Fantasy Baseball Picks: Top Plays for Thursday 8/6/26

Published:

By: Blake Krass

The MLB season is humming along. There are far more ways to get involved in the action than just via traditional betting. One of the more unique features on DraftKings this year is Pick6 Fantasy Baseball!

Here are my top Pick6 plays for today’s MLB slate.

DraftKings MLB Pick6 Plays

Bobby Witt Jr. More Than 1.5 Total Bases

Bobby Witt Jr. is batting .281 with an .803 OPS this season. Witt has consistently been one of the best hitters in baseball over the past few seasons, and while he hasn’t been at his peak in 2026, it’s been another strong showing. Witt missed a couple of weeks of action at the end of July and just made his return to the lineup. Witt announced his return with a three-hit night on Tuesday against the Twins. He should keep that hot return going against Bailey Ober. The Twins right-hander has a 4.45 ERA on the season and should struggle against Witt. Bobby Witt Jr. has 28 career at-bats against Ober. In those meetings, he is batting .429 with a 1.179 OPS. Witt should get a couple of hits in this game and cruise over this number.


Bryce Harper More Than 2.5 Hits + Runs + RBIs

Miles Mikolas has had a rough year on the mound. He has a 5.67 ERA and a 1.35 WHIP in 2026. Left-handers are batting .293 against Mikolas this year, and Bryce Harper should crush him tonight. Harper has an .857 OPS, despite struggling in left-on-left matchups. Against right-handers like Mikolas, Harper is batting .282 with a .989 OPS. Harper has hit 20 of his 24 home runs this season against righties. Meanwhile, Miles Mikolas ranks 88th out of the 89 pitchers who have thrown at least 100 innings this season in home runs allowed per nine. Harper has a career 1.024 OPS against Mikolas and should make the most of this matchup.


Ceddanne Rafaela More Than 0.5 Hits

Ceddanne Rafaela is one of the hottest hitters in baseball during this Red Sox winning streak. It has been a breakout season for Rafaela, who is batting .287 with an .804 OPS in 2026. Over the past 15 days, however, he has been on another level. He is batting .328 with a 1.091 OPS over that stretch. He should keep it going tonight against Luis Castillo. This will be Castillo’s first start as a member of the White Sox after getting traded from Seattle. It has been a rough year for Castillo, who has a 5.06 ERA and a 1.39 WHIP. Rafaela has a base hit in nine of his past 10 games and should get another one on the board against Castillo and the White Sox.


What is DraftKings Pick6?

Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of 2+ players and select whether you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.

How to Play

Create a Pick Set

Create a Pick Set by choosing 2+ players from the same sport and Pick Group (a set of picks available from a group of competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you can not pick the same player twice, and you must pick players from at least two different teams.

Enter an Amount

Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.

Sweat Your Picks

When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.

Compete for Prizes

Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.


Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!


Gambling Problem? Call 1-800-GAMBLER. Must be at least 18 years or older. Higher age limits may apply in some states. Eligibility restrictions apply. Valid only in states where DraftKings Pick6 operates. Void where prohibited. For entertainment purposes only. Winning a contest on DraftKings depends on knowledge and exercise of skill. See terms at pick6.draftkings.com.


Blake Krass has contributed to DraftKings since 2024, and is a content creator with a specialty in sports betting. Blake primarily focuses on college football and NFL coverage but will also be covering college basketball, the NBA, MLB and more. Prior to arriving at DK, Blake was a sports betting writer for The Action Network.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.