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Best NRFI Bets Today: No Run First Inning MLB Picks For Sunday 5/24/26

Best NRFI Bets Today: No Run First Inning MLB Picks For Sunday 5/24/26

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By: Dan Johnson

Who can suppress all the greatest forces of competitive volatility for six outs? The juicy NRFI—a wager on sequencing, on command showing up immediately, on hitters needing just one more pitch to calibrate. Even this early in the season, the modern game is louder than ever—exit velocity, launch angle, damage on contact. But the first inning still lives in a narrower band, where timing lags just enough behind power to create silence.

With that in mind, here are my top three NRFI picks for Sunday’s full slate of MLB action.

Padres vs. Athletics NRFI (-135)

Petco Park is built for this kind of first-inning play. San Diego has allowed a first-inning run in only 19.61% of games, one of the best opponent-YRFI prevention marks in MLB, and its home park remains one of the league’s better run-suppressing environments. Michael King gives the Padres the right arm for the top of the frame, entering at 4-2 with a 2.31 ERA and 59 strikeouts, while Luis Medina counters for Oakland at 1-1 with a 2.41 ERA and 18 strikeouts. The A’s have more power than their reputation suggests, but San Diego just held them scoreless in a 2-0 game, and the Padres’ late-May offense has been uneven enough that Medina does not need perfection to clear the first three outs. The shape is simple: King’s strikeout profile against an Oakland top third that can run hot and cold, Medina’s current run prevention against a Padres lineup that has not consistently turned name value into immediate traffic, and Petco shaving carry off the first hard contact of the afternoon.

Royals vs. Mariners NRFI (-130)

Seattle and Kansas City bring enough starter quality and offensive drag to justify a first-inning under. Bryan Woo enters at 4-2 with a 3.51 ERA and 55 strikeouts, while Seth Lugo sits at 1-4 with a 3.68 ERA and 51 strikeouts. Kansas City’s recent offense has been the larger part of the handicap: before Saturday’s bounce-back, the Royals had lost 10 of 11, averaged only 2.3 runs across that stretch and were shut out 2-0 by Seattle while producing just four singles. Saturday’s early rally against George Kirby came with soft contact and defensive mess, not a clean top-order power ambush. Woo’s strike-throwing gives him a path through Bobby Witt Jr. and the top of the Royals order without gifting the inning, and Lugo’s command keeps Seattle from turning the first three hitters into a free baserunner-and-gap-shot problem. With both starters carrying strikeout totals above 50 and neither offense profiling as a first-inning machine, -130 is fair for the no-run angle.

Giants vs. White Sox NRFI (-130)

Oracle Park is the anchor here. San Francisco owns an 80.77% NRFI rate, one of the strongest marks on the board, and the ballpark gives pitchers extra room to survive loud contact. Chicago has more first-inning danger than the Giants, especially with the White Sox power bats capable of ambushing mistakes, but that profile plays differently in San Francisco than it does in a smaller, warmer yard. Noah Schultz brings volatility with a 4.93 ERA and 32 strikeouts, while Robbie Ray enters at 3-6 with a 4.28 ERA and 50 strikeouts. The numbers are not spotless, but Ray’s strikeout base still matters against a Chicago lineup that leans heavily on damage swings, and Oracle can turn a deep fly into a harmless out. San Francisco’s offense remains inconsistent enough to trust Schultz for one clean inning, especially with the Giants’ top-third production still lagging behind the names. The price stays usable because the venue, Giants’ season-long NRFI profile and both starters’ strikeout ability all point toward a quiet first.

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Dan Johnson has been an editor, writer, and analyst for DraftKings and DraftKings Network since 2024. He’s previously held editorial posts at The Paris Review, Macmillan Publishers, Bedford/St. Martin’s Press, ASSIGNMENT Magazine, and FantasySixPack. You can find his various editorial work & writing (sports-related and non-) at all of the above.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user (my username is thegreatdansby9) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.