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MLB Best Bets Today: Top Expert Picks and Predictions for Wednesday 4/29/26

MLB Best Bets Today: Top Expert Picks and Predictions for Wednesday 4/29/26

Sports Betting Picks MLB DraftKings Sportsbook Insights

Published:

By: DK.Network.Editors

Looking for the best MLB picks today? Get top bets, player props and expert predictions for Wednesday’s games from DraftKings Network analysts.

To see all DraftKings betting analysis, head over to the DraftKings Network sports betting picks page!

Check out the numerous MLB betting markets available on DraftKings Sportsbook!

Garion Thorne: Top Home Run Props

Picks below! Read Garion’s full betting analysis here: MLB Best Bets: Top Home Run Props for Wednesday 4/29/26

Yordan Alvarez 1+ Home Run (+297)

Elly De La Cruz 1+ Home Run (+316)

Garion Thorne: Angels at White Sox prediction, pick

Pick below! Read Garion’s full betting analysis here: Los Angeles Angels at Chicago White Sox prediction, pick for Wednesday 4/29/26

Best Bet: White Sox ML (+100)

Garion Thorne: Rays at Guardians prediction, pick

Pick below! Read Garion’s full betting analysis here: Tampa Bay Rays at Cleveland Guardians prediction, pick for Wednesday 4/29/26

Best Bet: Under 6.5 (-108)

DK.Network.Editors

DraftKings promoters may sometimes play on personal accounts in the games that advice is offered on. Personal views on the games and strategies above do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. DraftKings promoters may also deploy different players and strategies than what is recommended above. DraftKings promoters do not have access to any non-public information.