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Best MLB Picks Today: Top Bets and Player Props for Wednesday 4/22/26

Best MLB Picks Today: Top Bets and Player Props for Wednesday 4/22/26

Published:

By: DK.Network.Editors

Get the best MLB picks today, including top bets, player props and predictions from the MLB Dugout Betting Group for Wednesday’s games.

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For up-to-date MLB betting information and data, check out both the DraftKings Sportsbook betting splits page and the DraftKings Sportsbook player props page!


Tim Finnegan

Parlay:

Aaron Judge 2+ Hits + Runs + RBIs (at BOS)

Matt Olson 2+ Hits + Runs + RBIs (at WAS)

Odds: +184

Tail this bet by clicking the odds above!

Analysis:

Parlay:

TOR Blue Jays at LA Angels –– NRFI

MIL Brewers at DET Tigers –– NRFI

MIN Twins at NY Mets –– NRFI

Odds: +421

Tail this bet by clicking the odds above!

Analysis:


Bryan Armetta

Parlay:

NY Yankees at BOS Red Sox –– NRFI

MIL Brewers at DET Tigers –– NRFI

Odds: +189

Tail this bet by clicking the odds above!

Analysis:


Brendan O’Sullivan

Parlay:

STL Cardinals at MIA Marlins –– OVER 8.5 Total Runs

HOU Astros at CLE Guardians –– OVER 8 Total Runs

BAL Orioles at KC Royals –– UNDER 9 Total Runs

Odds: +602

Tail this bet by clicking the odds above!

Analysis:


DraftKings promoters may sometimes play on personal accounts in the games that advice is offered on. Personal views on the games and strategies above do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. DraftKings promoters may also deploy different players and strategies than what is recommended above. DraftKings promoters do not have access to any non-public information.