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Best MLB Picks Today: Top Bets and Player Props for April 21, 2026

Best MLB Picks Today: Top Bets and Player Props for April 21, 2026

Published:

By: DK.Network.Editors

Looking for the best MLB picks today? DraftKings Network analysts share their top bets, player props and predictions from the MLB Dugout Betting Group for Tuesday’s slate.

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For up-to-date MLB betting information and data, check out both the DraftKings Sportsbook betting splits page and the DraftKings Sportsbook player props page!


Tim Finnegan

Parlay:

Aaron Judge 2+ Hits + Runs + RBIs (at BOS)

Austin Riley 2+ Hits + Runs + RBIs (at WAS)

Odds: +203

Tail this bet by clicking the odds above!

Analysis:

Parlay:

MIN Twins at NY Mets –– NRFI

LA Dodgers at SF Giants –– NRFI

Odds: +185

Tail this bet by clicking the odds above!

Analysis:


Ryan Wohl

Same Game Parlay (SGP):

HOU Astros at CLE Guardians

Jose Ramirez 2+ Total Bases

Ryan Weiss 4+ Strikeouts Thrown

Odds: +375

Tail this bet by clicking the odds above!

Analysis:


DraftKings promoters may sometimes play on personal accounts in the games that advice is offered on. Personal views on the games and strategies above do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. DraftKings promoters may also deploy different players and strategies than what is recommended above. DraftKings promoters do not have access to any non-public information.