The 2026 MLB season is in full swing with 10 games taking place across Monday’s slate. The Houston Astros and Seattle Mariners kick off the action in a 4:10 p.m. ET matchup, leading up to a 10:10 p.m. ET game between the New York Mets and Los Angeles Dodgers.
There are plenty of ways to get in on the action on DraftKings. One of the more unique ways to play this year is with Pick6 Fantasy Baseball!
Let’s take a look at my top Pick6 plays for Monday’s action. You simply choose whether each set statistic will be more or less than the set number. With the stage set, here are my top picks on today’s MLB slate.
Gunnar Henderson More Than 1.5 Hits, Runs, & RBIs
Gunnar Henderson has burst onto the MLB stage these past few years, looking the part of a budding superstar. He has picked up right where he left off this season, crushing six home runs across his first 15 games. The 24-year-old is hitting .242 with a .919 OPS and enters this matchup on a six-game hitting streak, including four homers and six RBIs.
Henderson should keep the momentum rolling against Diamondbacks starter Ryne Nelson. The right-hander has allowed a 52.2% hard-hit rate and given up multiple home runs in two of his three starts this season. Henderson is also 2-for-4 with a home run in his career against the struggling Nelson.
Cristopher Sanchez More Than 6.5 Strikeouts Thrown
It has been an uneasy start to the Phillies season, and Cristopher Sanchez will attempt to stem the tide in Monday’s series opener against the Cubs. Across three starts this season, Sanchez has posted a 1.65 ERA with 23 strikeouts (12.67 K/9) over 16.1 innings. He led MLB pitchers with an 8.0 bWAR last season and has been elevated to Philadelphia’s ace while Zack Wheeler continues his rehab. The 29-year-old has cleared 6.5 strikeouts in two of his first three starts.
He should continue shoving against the Cubs, who rank 22nd in hits and 16th in strikeouts this season. Sanchez has yet to reach his peak, still finding ways to limit damage and get outs. He also recorded a 10.60 K/9 at home last season, compared to 8.37 on the road. With the Philly crowd behind him, expect Sanchez to get the Phillies back on track.
Drake Baldwin More Than 1.5 Total Bases
It has been an impressive start to the season for Atlanta’s standout catcher Drake Baldwin. The reigning Rookie of the Year is hitting .303 with a .930 OPS and five home runs across his first 16 games. Baldwin leads MLB with 15 runs scored and 17 RBIs, also racking up 20 hits and 37 total bases. He has 11 hits in his past seven games with 18 total bases during that stretch.
The Braves open a series on Monday against the Marlins with Eury Perez on the mound. He holds a 5.06 ERA across his first three starts, having already allowed four home runs. Baldwin is 2-for-4 with a pair of no-doubters in his career against the sputtering right-hander. Back the young Braves star to keep raking in the favorable matchup.
Garrett Crochet More than 7.5 Strikeouts Thrown
After an ugly start to the season, the Boston Red Sox have started to find their footing. They’ve won four of their last five games and will look to keep building with ace Garrett Crochet on the bump. The two-time All-Star has not played his best to start the season, posting a 3.12 ERA across 17.1 innings. Still, he’s racked up 22 strikeouts for an impressive 29.7 K-rate.
He’ll face a Twins team that sits in MLB’s bottom ten with a brutal 25.3% strikeout percentage. Crochet led the league with 255 strikeouts (11.18 K/9) last season and has still tallied at least seven strikeouts in all three of his starts. One of the top strikeout artists in the game, expect Crochet to sit down more than eight Twins batters Monday night.
Shea Langeliers More Than 1.5 Total Bases
It has been a scorching start to the season for Shea Langeliers. The Athletics catcher is hitting .293 with a .914 OPS through his first 14 games played. Langeliers is 6-for-8 across his past four games — with two doubles — and he also had five home runs in his first six games of 2026.
The A’s will take on the Texas Rangers with Nathan Eovaldi on the mound. The veteran right-hander has struggled so far, posting a 7.98 ERA with four home runs allowed. Langeliers is 4-for-12 (.333) with a pair of doubles and a home run against him in his career. Expect the catcher to extend his hitting streak and tally multiple total bases in Monday’s matchup.
Brandon Nimmo More Than 1.5 Total Bases
On the other side of the Athletics-Rangers matchup, Brandon Nimmo is in a prime position to add to his early-season production. The former Mets standout is hitting .367 with a 1.033 OPS and three home runs across his first 15 games with Texas. With warm weather and a little wind, expect Nimmo’s bat to stay hot at the hitter-friendly Sutter Health Park.
Taking the ball for the A’s is Luis Severino, who enters with a 5.40 ERA across 13.1 innings in 2026. Nimmo is an impressive 5-for-10 with two doubles and a home run in his career against his former teammate. Nimmo has eight hits over his past four games, good for 16 total bases. Expect him to pick up at least two more on Monday.
What is DraftKings Pick6?
Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of 2+ players and select whether you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.
How to Play
Create a Pick Set
Create a Pick Set by choosing 2+ players from the same sport and Pick Group (a set of picks available from a group of set competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you cannot pick the same player twice and must pick players from at least two different teams.
Enter an Amount
Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.
Sweat Your Picks
When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.
Compete for Prizes
Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.
Play at DraftKings Pick6 or by downloading the DraftKings Pick6 app on Apple or Google!
